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7/13/2022 1:34:43 AM | Browse: 443 | Download: 1341
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Received |
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2022-02-01 04:58 |
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Peer-Review Started |
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2022-02-01 04:59 |
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First Decision by Editorial Office Director |
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2022-04-17 08:04 |
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Return for Revision |
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2022-04-17 08:04 |
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Revised |
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2022-04-29 15:55 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-06-01 02:58 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-06-03 21:34 |
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Articles in Press |
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2022-06-03 21:34 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-07-02 07:41 |
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Publish the Manuscript Online |
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2022-07-13 01:27 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Efficacy of neoadjuvant chemotherapy for initially resectable colorectal liver metastases: A retrospective cohort study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kazuhisa Takeda, Yu Sawada, Yasuhiro Yabushita, Yuki Honma, Takafumi Kumamoto, Jun Watanabe, Ryusei Matsuyama, Chikara Kunisaki, Toshihiro Misumi and Itaru Endo |
| Funding Agency and Grant Number |
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| Corresponding Author |
Kazuhisa Takeda, PhD, Assistant Professor, Gastroenterological Center, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, Japan. kazu1968@yokohama-cu.ac.jp |
| Key Words |
Colorectal neoplasms; Neoadjuvant therapy; Neoplasm metastasis; Prognosis; Risk factors; Survival |
| Core Tip |
Hepatectomy is the mainstay of treatment for patients with colorectal liver metastases (CRLMs). However, there are cases of early recurrence after upfront hepatectomy alone. In selected high-risk patients, neoadjuvant chemotherapy (NAC) may improve long-term survival. Although several studies have identified risk factors for recurrence and prognosis after hepatectomy for CRLMs, they could not show a benefit of NAC for resectable CRLMs. This article demonstrated the effectiveness of NAC for initially resectable CRLMs, based on risk stratification according to prognostic factors. |
| Publish Date |
2022-07-13 01:27 |
| Citation |
Takeda K, Sawada Y, Yabushita Y, Honma Y, Kumamoto T, Watanabe J, Matsuyama R, Kunisaki C, Misumi T, Endo I. Efficacy of neoadjuvant chemotherapy for initially resectable colorectal liver metastases: A retrospective cohort study. World J Gastrointest Oncol 2022; 14(7): 1281-1294
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| URL |
https://www.wjgnet.com/1948-5204/full/v14/i7/1281.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v14.i7.1281 |
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