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5/24/2022 9:30:38 AM | Browse: 246 | Download: 868
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Received |
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2022-01-08 18:16 |
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Peer-Review Started |
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2022-01-08 18:18 |
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To Make the First Decision |
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Return for Revision |
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2022-02-21 08:44 |
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Revised |
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2022-03-04 19:29 |
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Second Decision |
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2022-04-29 03:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-04-30 07:41 |
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Articles in Press |
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2022-04-30 07:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-04-16 23:29 |
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Typeset the Manuscript |
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2022-05-18 03:16 |
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Publish the Manuscript Online |
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2022-05-24 08:03 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Minireviews |
| Article Title |
Multidisciplinary basic and clinical research of acute kidney injury with COVID-19: Pathophysiology, mechanisms, incidence, management and kidney transplantation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mohamed Wishahi and Nabawya M Kamal |
| Funding Agency and Grant Number |
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| Corresponding Author |
Mohamed Wishahi, MD, PhD, Doctor, Professor, Department of Urology, Theodor Bilharz Research Institute , Embaba, Giza, Cairo 12411, Egypt. moh.weshahy@gmail.com |
| Key Words |
Acute kidney injury; COVID-19; SARS-CoV-2; Kidney transplantation; Dialysis; Immunosuppressant; Intensive care unit; Mortality; Cytokine storm |
| Core Tip |
Acute kidney injury (AKI) in patients with coronavirus disease 2019 (COVID-19) is initiated by multifactorial events including direct viral effect, cardiac causes, thromboembolic phenomenon and cytokine storm. AKI is attributed to collapsing glomerulopathy, acute tubular necrosis and mitochondrial dysfunction. Management of AKI is multidisciplinary dependent on severity of COVID-19, associated comorbidities, intensive care unit admission and artificial ventilation. Management is initial control of fluid balance and in severe cases an early initiation of renal replacement and extracorporeal organ support which would support the organs and prevent disease progression. Kidney transplantation patients are at risk of developing AKI due to the state of their immunocompromised status caused by regular use of immunosuppressants; this situation indicates the adjustment of immunosuppressors in the condition of treatment of cytokine storm with corticosteroids. |
| Publish Date |
2022-05-24 08:03 |
| Citation |
Wishahi M, Kamal NM. Multidisciplinary basic and clinical research of acute kidney injury with COVID-19: Pathophysiology, mechanisms, incidence, management, and kidney transplantation. World J Nephrol 2022; 11(3): 105-114 |
| URL |
https://www.wjgnet.com/2220-6124/full/v11/i3/105.htm |
| DOI |
https://dx.doi.org/10.5527/wjn.v11.i3.105 |
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