Publication Name	World Journal of Clinical Oncology
Manuscript ID	7492
Country	United States

Received	2013-11-22 07:44
Peer-Review Started	2013-11-22 11:37
To Make the First Decision	2014-02-27 10:16
Return for Revision	2014-03-04 20:39
Revised	2014-03-05 00:38
Second Decision	2014-05-16 17:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-16 17:52
Articles in Press	2014-05-23 09:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-24 14:19
Publish the Manuscript Online	2014-12-11 14:23

ISSN	2218-4333 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Role of FDG PET-CT in evaluation of locoregional nodal disease for initial staging of breast cancer
Manuscript Source	Invited Manuscript
All Author List	Yiyan Liu
Funding Agency and Grant Number
Corresponding Author	Yiyan Liu, MD, PhD Assocaite Professor Department of Radiology New Jersey Medical School Rutgers University 150 Bergen Street, H141 Newark, New Jersey 07103 U.S.A liuyl@njms.rutgers.edu
Key Words	Breast cancer; FDG PET/CT; Locoregional nodal disease; Axillary lymph node; Internal mammary lymph node
Core Tip	The presence and extent of locoregional nodal metastasis at diagnosis is the single most important prognostic factor in breast cancer. The predominant lymphatic drainage pathway from the breast cancer is toward the axilla. FDG PET/CT is a good predictor of axillary disease and correlates well with SLNB. FDG PET/CT may help to identify patients with high axillary lymph node burden who could then move directly to ALND and would not require the additional step of SLNB. However, FDG PET/CT cannot replace SLNB or ALND due to unsatisfactory sensitivity secondary to the limitation of its spatial resolution. The internal mammary node (IMN) involvement is of prognostic significance in breast cancer, and IMN metastasis has been associated with higher rate of distant metastasis and lower overall survival rates. Limited preliminary data indicated that FDG PET/CT plays a role in identification of positive IMN, and it is superior to conventional imaging modalities.
Publish Date	2014-12-11 14:23
Citation	Liu Y. Role of FDG PET-CT in evaluation of locoregional nodal disease for initial staging of breast cancer. World J Clin Oncol 2014; 5(5): 982-989
URL	http://www.wjgnet.com/2218-4333/full/v5/i5/982.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i5.982

Full Article (PDF)	WJCO-5-982.pdf
Full Article (Word)	WJCO-5-982.doc
Manuscript File	7492-Review.doc
Answering Reviewers	7492-Answering reviewers.pdf
Copyright License Agreement	7492-Copyright assignment.pdf
Peer-review Report	7492-Peer review(s).pdf
Scientific Editor Work List	7492-Scientific editor work list.pdf