Publication Name	World Journal of Translational Medicine
Manuscript ID	74949
Country	India

Received	2022-01-12 06:24
Peer-Review Started	2022-01-12 06:26
To Make the First Decision
Return for Revision	2022-02-08 10:44
Revised	2022-03-05 14:27
Second Decision	2022-06-01 02:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-06-03 21:42
Articles in Press	2022-06-03 21:42
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-05-25 17:49
Typeset the Manuscript	2022-06-13 09:04
Publish the Manuscript Online	2022-06-24 07:19

ISSN	2220-6132 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Minireviews
Article Title	Current progress and emerging technologies for generating extra-pancreatic functional insulin producing cells
Manuscript Source	Unsolicited Manuscript
All Author List	Md Aejaz Habeeb, Sandeep Kumar Vishwakarma, Safwaan Habeeb and Aleem Ahmed Khan
Funding Agency and Grant Number
Corresponding Author	Md Aejaz Habeeb, MBBS, MD, PhD, Centre for Liver Research and Diagnostics, Deccan College of Medical Sciences, Kanchanbagh, DMRL X Road, Hyderabad 500058, Telangana, India. aejazhabeeb@hotmail.com
Key Words	Diabetes mellitus; Cell-based therapy; Insulin producing cells; Extra-pancreatic sources; Biomaterials; Tissue engineering
Core Tip	The currently accepted available treatment strategies for uncontrolled diabetes mellitus (DM) are pancreas and islet transplantation. However, these strategies are limited due to unavailability of quality pancreas/islet donors, life-long need of immunosuppressant and associated complications. Exogenous insulin administration is one of the clinically established options for the patients with type 1 DM. Liver could be an appropriate extra-pancreatic source to isolate produce number of insulin producing cells due to similar embryonic developmental origin. The furthermost need to develop more effective diabetes cell-based therapies lies in the advancements of robust sensitive micro and nanodevices for exogenous insulin-delivery.
Publish Date	2022-06-24 07:19
Citation	Habeeb MA, Vishwakarma SK, Habeeb S, Khan AA. Current progress and emerging technologies for generating extrapancreatic functional insulin-producing cells. World J Transl Med 2022; 10(1): 1-13
URL	https://www.wjgnet.com/2220-3230/full/v10/i1/1.htm
DOI	https://dx.doi.org/10.5528/wjtm.v10.i1.1

Full Article (PDF)	WJTM-10-1.pdf
Full Article (Word)	WJTM-10-1.docx
Manuscript File	74949_Auto_Edited-JRF-Kerr C-LS.docx
Answering Reviewers	74949-Answering reviewers.pdf
Audio Core Tip	74949-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	74949-Conflict-of-interest statement.pdf
Copyright License Agreement	74949-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	74949-Language certificate.pdf
Peer-review Report	74949-Peer-review(s).pdf
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Scientific Editor Work List	74949-Scientific editor work list.pdf
CrossCheck Report	74949-CrossCheck report.pdf
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