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6/17/2022 6:23:41 AM | Browse: 58 | Download: 81
Publication Name World Journal of Orthopedics
Manuscript ID 75179
Country/Territory Poland
Received
2022-01-18 20:30
Peer-Review Started
2022-01-18 20:32
To Make the First Decision
Return for Revision
2022-03-24 09:32
Revised
2022-04-04 12:04
Second Decision
2022-05-06 02:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-05-07 00:42
Articles in Press
2022-05-07 00:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-06-05 12:27
Publish the Manuscript Online
2022-06-17 03:54
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Sport Sciences
Manuscript Type Basic Study
Article Title Content of blood cell components, inflammatory cytokines and growth factors in autologous platelet-rich plasma obtained by various methods
Manuscript Source Unsolicited Manuscript
All Author List Maciej Dejnek, Jarosław Witkowski, Helena Moreira, Sylwia Płaczkowska, Piotr Morasiewicz, Paweł Reichert and Aleksandra Królikowska
Funding Agency and Grant Number
Funding Agency Grant Number
Wroclaw Medical University as a Regional Center of Excellence in the field of medical sciences and health sciences RID.Z501.20.008
Corresponding Author Maciej Dejnek, MD, Research Scientist, Surgeon, Department of Trauma and Hand Surgery, Wroclaw Medical University, ul. Borowska 213, Wroclaw 50-556, Poland. maciej.dejnek@student.umed.wroc.pl
Key Words Platelet-rich plasma; Cytokines; Chemokines; Growth factors
Core Tip The presented study showed important differences between blood cell components and levels of selected growth factors and inflammatory cytokines in platelet-rich plasma obtained with four different commercial preparation systems in a single-donor model. The range of cytokines analyzed far exceeded the ranges investigated in earlier publications. This was also the first study to pay attention to the repeatability of the quality of the obtained PRP. New positive correlations were found between platelet content in PRP and several cytokines (HGF, IL-1β, MCP-1, IL-8, IL-18). The demonstrated positive correlation between red blood cell content in PRP and cytokines has never been described before.
Publish Date 2022-06-17 03:54
Citation Dejnek M, Witkowski J, Moreira H, Płaczkowska S, Morasiewicz P, Reichert P, Królikowska A. Content of blood cell components, inflammatory cytokines and growth factors in autologous platelet-rich plasma obtained by various methods. World J Orthop 2022; 13(6): 587-602
URL https://www.wjgnet.com/2218-5836/full/v13/i6/587.htm
DOI https://dx.doi.org/10.5312/wjo.v13.i6.587
Full Article (PDF) WJO-13-587.pdf
Full Article (Word) WJO-13-587.docx
Manuscript File 75179_Auto_Edited.docx
Answering Reviewers 75179-Answering reviewers.pdf
Audio Core Tip 75179-Audio core tip.mp3
Biostatistics Review Certificate 75179-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 75179-Conflict-of-interest statement.pdf
Copyright License Agreement 75179-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 75179-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 75179-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 75179-Language certificate.pdf
Supplementary Material 75179-Supplementary material.pdf
Peer-review Report 75179-Peer-review(s).pdf
Scientific Misconduct Check 75179-Bing-Wang LL-2.png
Scientific Editor Work List 75179-Scientific editor work list.pdf