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8/3/2022 8:55:07 AM | Browse: 17 | Download: 29
Publication Name World Journal of Gastroenterology
Manuscript ID 75195
Country/Territory United States
Received
2022-01-18 02:18
Peer-Review Started
2022-01-18 02:19
To Make the First Decision
Return for Revision
2022-04-11 06:54
Revised
2022-04-24 14:55
Second Decision
2022-07-01 03:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-07-06 03:12
Articles in Press
2022-07-06 03:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-07-25 02:39
Publish the Manuscript Online
2022-08-03 07:54
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Mechanistic and functional extrapolation of SET and MYND domain-containing protein 2 to pancreatic cancer
Manuscript Source Invited Manuscript
All Author List Eid Alshammari, Ying-Xue Zhang and Zhe Yang
Funding Agency and Grant Number
Corresponding Author Zhe Yang, PhD, Associate Professor, Department of Biochemistry, Microbiology, and Immunology, Wayne State University School of Medicine , 540 E Canfield St, Detroit, MI 48201, United States. zyang@med.wayne.edu
Key Words Pancreatic ductal adenocarcinoma; Protein lysine methyltransferase; Histone/non-histone methylation; Oncogenic signaling pathways; Methyltransferase inhibitors
Core Tip The broad substrate specificity of SET and MYND domain-containing protein 2 (SMYD2) and its involvement in diverse oncogenic signaling pathways in numerous cancers have provided a wealth of information that could be extrapolated to the pancreatic ductal adenocarcinoma (PDAC) research field to expand our understanding of SMYD2 in PDAC development. This review not only discusses the known roles of SMYD2 in PDAC initiation and progression, but also aims to capitalize on a rich body of knowledge with respect to SMYD2’s involvement in various signaling cascades to develop new hypotheses about the mechanisms of driving PDAC tumor growth and metastasis.
Publish Date 2022-08-03 07:54
Citation Alshammari E, Zhang YX, Yang Z. Mechanistic and functional extrapolation of SET and MYND domain-containing protein 2 to pancreatic cancer. World J Gastroenterol 2022; 28(29): 3753-3766
URL https://www.wjgnet.com/1007-9327/full/v28/i29/3753.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i29.3753
Full Article (PDF) WJG-28-3753.pdf
Full Article (Word) WJG-28-3753.docx
Manuscript File 75195_Auto_Edited-LS.docx
Answering Reviewers 75195-Answering reviewers.pdf
Audio Core Tip 75195-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 75195-Conflict-of-interest statement.pdf
Copyright License Agreement 75195-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 75195-Language certificate.pdf
Peer-review Report 75195-Peer-review(s).pdf
Scientific Misconduct Check 75195-Bing-Chen YL-2.png
Scientific Editor Work List 75195-Scientific editor work list.pdf