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9/9/2022 1:13:12 PM | Browse: 45 | Download: 50
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 75248
Country/Territory United States
Received
2022-01-20 01:53
Peer-Review Started
2022-01-20 01:54
To Make the First Decision
Return for Revision
2022-04-17 18:44
Revised
2022-04-26 06:25
Second Decision
2022-08-03 02:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-08-07 17:12
Articles in Press
2022-08-07 17:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-09-02 02:02
Publish the Manuscript Online
2022-09-09 12:48
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Meta-Analysis
Article Title Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data
Manuscript Source Unsolicited Manuscript
All Author List Jihad Aljabban, Michael Rohr, Saad Syed, Eli Cohen, Naima Hashi, Sharjeel Syed, Kamal Khorfan, Hisham Aljabban, Vincent Borkowski, Michael Segal, Mohamed Mukhtar, Mohammed Mohammed, Emmanuel Boateng, Mary Nemer, Maryam Panahiazar, Dexter Hadley, Sajid Jalil and Khalid Mumtaz
Funding Agency and Grant Number
Corresponding Author Jihad Aljabban, MD, MSc, Academic Research, Doctor, Department of Medicine, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, Madison, WI 53792, United States. jaljabban@uwhealth.org
Key Words Hepatitis B virus; Hepatocellular carcinoma; Genomics; Meta-analysis
Core Tip Hepatitis B virus (HBV) is a cause of hepatocellular carcinoma (HCC). Interestingly, this process is not necessarily mediated through cirrhosis and may in fact involve oncogenic processes. Prior studies have suggested specific oncogenic gene expression pathways were affected by viral regulatory proteins. Thus, identifying these genes and associated pathways could highlight predictive factors for HCC transformation, and has implications in early diagnosis and treatment. Our manuscript leverages big data to offer key insights to oncogenesis of HBV infection in HCC. We were able to dissect key genetic drivers to disease and namely demonstrate a newfound role for rab-like protein 6 and homeobox A10.
Publish Date 2022-09-09 12:48
Citation Aljabban J, Rohr M, Syed S, Cohen E, Hashi N, Syed S, Khorfan K, Aljabban H, Borkowski V, Segal M, Mukhtar M, Mohammed M, Boateng E, Nemer M, Panahiazar M, Hadley D, Jalil S, Mumtaz K. Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data. World J Gastrointest Oncol 2022; 14(9): 1856-1873
URL https://www.wjgnet.com/1948-5204/full/v14/i9/1856.htm
DOI https://dx.doi.org/10.4251/wjgo.v14.i9.1856
Full Article (PDF) WJGO-14-1856.pdf
Full Article (Word) WJGO-14-1856.docx
Manuscript File 75248_Auto_Edited-LM.docx
Answering Reviewers 75248-Answering reviewers.pdf
Audio Core Tip 75248-Audio core tip.mp3
Biostatistics Review Certificate 75248-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 75248-Conflict-of-interest statement.pdf
Copyright License Agreement 75248-Copyright license agreement.pdf
Supplementary Material 75248-Supplementary material.pdf
Peer-review Report 75248-Peer-review(s).pdf
Scientific Misconduct Check 75248-Bing-Wang JJ-2.png
Scientific Editor Work List 75248-Scientific editor work list.pdf