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7/27/2022 1:20:42 PM | Browse: 27 | Download: 34
Publication Name World Journal of Hepatology
Manuscript ID 76510
Country/Territory India
Received
2022-03-23 13:17
Peer-Review Started
2022-03-23 13:19
To Make the First Decision
Return for Revision
2022-04-28 08:20
Revised
2022-05-13 09:03
Second Decision
2022-06-29 03:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-07-06 22:08
Articles in Press
2022-07-06 22:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-07-18 00:35
Publish the Manuscript Online
2022-07-27 13:17
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Effect of thrombocytopenia and platelet transfusion on outcomes of acute variceal bleeding in patients with chronic liver disease
Manuscript Source Invited Manuscript
All Author List Sagnik Biswas, Manas Vaishnav, Piyush Pathak, Deepak Gunjan, Soumya Jagannath Mahapatra, Saurabh Kedia, Gyanranjan Rout, Bhaskar Thakur, Baibaswata Nayak, Ramesh Kumar and Shalimar
Funding Agency and Grant Number
Corresponding Author Shalimar, MBBS, MD, Additional Professor, Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110029, New Delhi 110029, Delhi, India. drshalimar@gmail.com
Key Words Gastrointestinal Hemorrhage; Platelet transfusion; Thrombocytopenia; Fresh frozen plasma; Portal hypertension; Mortality
Core Tip This is a retrospective study to assess the impact of thrombocytopenia at presentation and that of platelet transfusion in the management of acute variceal bleeding in patients with chronic liver disease. Ten percent of patients received platelet transfusions and were found to have significantly higher rebleed rates on day 5 and 42 after the index bleeding episode but did not result in significantly higher mortality rates in these patients. On multivariate analysis, platelet transfusion was an independent risk factor for 42-d rebleeding, while hepatic encephalopathy was a significant risk factor for 42-d mortality.
Publish Date 2022-07-27 13:17
Citation Biswas S, Vaishnav M, Pathak P, Gunjan D, Mahapatra SJ, Kedia S, Rout G, Thakur B, Nayak B, Kumar R, Shalimar. Effect of thrombocytopenia and platelet transfusion on outcomes of acute variceal bleeding in patients with chronic liver disease. World J Hepatol 2022;14(7): 1421-1437
URL https://www.wjgnet.com/1948-5182/full/v14/i7/1421.htm
DOI https://dx.doi.org/10.4254/wjh.v14.i7.1421
Full Article (PDF) WJH-14-1421.pdf
Full Article (Word) WJH-14-1421.docx
Manuscript File 76510_Auto_Edited-LM.docx
Answering Reviewers 76510-Answering reviewers.pdf
Audio Core Tip 76510-Audio core tip .mp3
Biostatistics Review Certificate 76510-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 76510-Conflict-of-interest statement.pdf
Copyright License Agreement 76510-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 76510-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 76510-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 76510-Language certificate.pdf
Supplementary Material 76510-Supplementary material.pdf
Peer-review Report 76510-Peer-review(s).pdf
Scientific Misconduct Check 76510-Bing-Liu JH-2.jpg
Scientific Misconduct Check 76510-CrossCheck.jpg
Scientific Editor Work List 76510-Scientific editor work list.pdf