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8/12/2022 11:50:09 AM | Browse: 543 | Download: 2005
Publication Name World Journal of Diabetes
Manuscript ID 77048
Country China
Received
2022-05-06 10:56
Peer-Review Started
2022-05-06 10:56
First Decision by Editorial Office Director
2022-05-30 09:21
Return for Revision
2022-05-30 09:21
Revised
2022-06-10 07:57
Publication Fee Transferred
Second Decision by Editor
2022-06-29 03:14
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2022-07-06 19:13
Articles in Press
2022-07-06 19:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-08-08 02:13
Publish the Manuscript Online
2022-08-12 11:48
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology & Pharmacy
Manuscript Type Basic Study
Article Title In vivo evaluation and mechanism prediction of anti-diabetic foot ulcer based on component analysis of Ruyi Jinhuang powder
Manuscript Source Unsolicited Manuscript
All Author List Xiu-Yan Li, Xiao-Tong Zhang, Yi-Cheng Jiao, Hang Chi, Ting-Ting Xiong, Wen-Jing Zhang, Mi-Nan Li and Yan-Hong Wang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82074025
Scientific Research Project of Heilongjiang Health Committee 2020-293
Scientific and Technological Innovation Project for College Students of Heilongjiang University of Chinese Medicine 2021-13
Corresponding Author Yan-Hong Wang, MD, Teacher, Key Laboratory of Basic and Application Research of Beiyao, Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, China. 799378826@qq.com
Key Words Ruyi Jinhuang powder; Diabetic foot ulcer; Mass spectrometry-chromatography; Network pharmacology; Hematoxylin-eosin staining; Components analysis
Core Tip Although some studies have suggested that Ruyi Jinhuang powder (RHP) has a therapeutic effect on diabetic foot ulcers (DFUs), few have used component analysis, investigated the mechanism of action, and utilized wound-healing experiments. The components of RHP were used to predict the mechanism of action, and wound healing was observed by establishing a DFU rat model to further prove the therapeutic effect of RHP on DFU to finally determine a possible mechanism of action.
Publish Date 2022-08-12 11:48
Citation Li XY, Zhang XT, Jiao YC, Chi H, Xiong TT, Zhang WJ, Li MN, Wang YH. In vivo evaluation and mechanism prediction of anti-diabetic foot ulcer based on component analysis of Ruyi Jinhuang powder. World J Diabetes 2022; 13(8): 622-642
URL https://www.wjgnet.com/1948-9358/full/v13/i8/622.htm
DOI https://dx.doi.org/10.4239/wjd.v13.i8.622
Full Article (PDF) WJD-13-622.pdf
Full Article (Word) WJD-13-622.docx