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8/12/2022 11:50:09 AM | Browse: 307 | Download: 1029
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Received |
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2022-05-06 10:56 |
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Peer-Review Started |
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2022-05-06 10:56 |
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To Make the First Decision |
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Return for Revision |
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2022-05-30 09:21 |
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Revised |
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2022-06-10 07:57 |
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Second Decision |
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2022-06-29 03:14 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-07-06 19:13 |
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Articles in Press |
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2022-07-06 19:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-08-08 02:13 |
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Publish the Manuscript Online |
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2022-08-12 11:48 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Basic Study |
| Article Title |
In vivo evaluation and mechanism prediction of anti-diabetic foot ulcer based on component analysis of Ruyi Jinhuang powder
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiu-Yan Li, Xiao-Tong Zhang, Yi-Cheng Jiao, Hang Chi, Ting-Ting Xiong, Wen-Jing Zhang, Mi-Nan Li and Yan-Hong Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82074025 |
| Scientific Research Project of Heilongjiang Health Committee |
2020-293 |
| Scientific and Technological Innovation Project for College Students of Heilongjiang University of Chinese Medicine |
2021-13 |
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| Corresponding Author |
Yan-Hong Wang, MD, Teacher, Key Laboratory of Basic and Application Research of Beiyao, Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, China. 799378826@qq.com |
| Key Words |
Ruyi Jinhuang powder; Diabetic foot ulcer; Mass spectrometry-chromatography; Network pharmacology; Hematoxylin-eosin staining; Components analysis |
| Core Tip |
Although some studies have suggested that Ruyi Jinhuang powder (RHP) has a therapeutic effect on diabetic foot ulcers (DFUs), few have used component analysis, investigated the mechanism of action, and utilized wound-healing experiments. The components of RHP were used to predict the mechanism of action, and wound healing was observed by establishing a DFU rat model to further prove the therapeutic effect of RHP on DFU to finally determine a possible mechanism of action. |
| Publish Date |
2022-08-12 11:48 |
| Citation |
Li XY, Zhang XT, Jiao YC, Chi H, Xiong TT, Zhang WJ, Li MN, Wang YH. In vivo evaluation and mechanism prediction of anti-diabetic foot ulcer based on component analysis of Ruyi Jinhuang powder. World J Diabetes 2022; 13(8): 622-642 |
| URL |
https://www.wjgnet.com/1948-9358/full/v13/i8/622.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v13.i8.622 |
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