Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	77263
Country	Italy

Received	2022-04-21 17:59
Peer-Review Started	2022-04-21 18:01
To Make the First Decision
Return for Revision	2022-07-14 18:49
Revised	2022-07-22 11:17
Second Decision	2022-08-22 03:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-08-25 21:01
Articles in Press	2022-08-25 21:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-09-16 08:08
Publish the Manuscript Online	2022-09-22 12:23

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Meta-Analysis
Article Title	Laparoscopic appendectomy, stump closure and endoloops: A meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Noemi Zorzetti, Augusto Lauro, Maria Irene Bellini, Samuele Vaccari, Barbara Dalla Via, Maurizio Cervellera, Roberto Cirocchi, Salvatore Sorrenti, Vito D’Andrea and Valeria Tonini
Funding Agency and Grant Number
Corresponding Author	Maria Irene Bellini, MD, PhD, Assistant Professor, Senior Lecturer, Department of Surgical Sciences, Sapienza University, Viale Regina Elena, Rome 00161, Italy. mariairene.bellini@uniroma1.it
Key Words	Acute appendicitis; Laparoscopic appendectomy; Endoloops; Stapler; Post-operative complications
Core Tip	Stump closure in the acute appendectomy setting could be performed via endoloop (EL) or endostapler use. The present meta-analysis assesses the experience of 996 patients consecutively treated in the department of Emergency General Surgery - St Orsola University Hospital, Bologna (Italy) and the evidence published in literature, confirming there is no superiority of a surgical method on how to perform the stump closure, with regards to wound infections, abdominal abscess, and total post-operative complications. Even when acute appendicitis is complicated, the routine use of EL is safe in most patients.
Publish Date	2022-09-22 12:23
Citation	Zorzetti N, Lauro A, Bellini MI, Vaccari S, Dalla Via B, Cervellera M, Cirocchi R, Sorrenti S, D’Andrea V, Tonini V. Laparoscopic appendectomy, stump closure and endoloops: A meta-analysis. World J Gastrointest Surg 2022; 14(9): 1060-1071
URL	https://www.wjgnet.com/1948-9366/full/v14/i9/1060.htm
DOI	https://dx.doi.org/10.4240/wjgs.v14.i9.1060

Full Article (PDF)	WJGS-14-1060.pdf
Full Article (Word)	WJGS-14-1060.docx
Manuscript File	77263_Auto_Edited-LS.docx
Answering Reviewers	77263-Answering reviewers.pdf
Audio Core Tip	77263-Audio core tip.wav
Biostatistics Review Certificate	77263-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	77263-Conflict-of-interest statement.pdf
Copyright License Agreement	77263-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	77263-Language certificate.pdf
Peer-review Report	77263-Peer-review(s).pdf
Scientific Misconduct Check	77263-Bing-Wang JJ-2.png
Scientific Editor Work List	77263-Scientific editor work list.pdf