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8/22/2022 12:21:31 PM | Browse: 332 | Download: 760
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Received |
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2022-05-02 10:37 |
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Peer-Review Started |
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2022-05-02 10:40 |
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To Make the First Decision |
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Return for Revision |
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2022-05-31 03:14 |
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Revised |
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2022-06-09 06:06 |
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Second Decision |
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2022-08-17 03:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-08-17 21:03 |
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Articles in Press |
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2022-08-17 21:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-08-08 16:19 |
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Typeset the Manuscript |
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2022-08-21 22:48 |
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Publish the Manuscript Online |
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2022-08-22 12:18 |
| ISSN |
2219-2824 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Minireviews |
| Article Title |
Probiotic treatment of Inflammatory Bowel Disease: Its extent and intensity
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Saheli Biswas and Ena Ray Banerjee |
| Funding Agency and Grant Number |
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| Corresponding Author |
Ena Ray Banerjee, DSc, PhD, Professor, Department of Zoology, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, West Bengal, India. enarb1@gmail.com |
| Key Words |
Oxidative stress; Inflammatory bowel disease; Probiotics; Therapy; Anti-oxidative activity |
| Core Tip |
Inflammatory bowel diseases (IBDs) are degenerative diseases that cause chronic inflammation in the intestine. The most prevalent therapy for IBD is conventional antibiotic therapy. Keeping the adverse effects of antibiotics in mind, researchers have shown that Streptococcus, Lactobacillus and Bifidobacterium are some of the most efficient antioxidative agents with respect to in vitro and in vivo activities. Probiotics individually or in combination play an important role in regulating superoxide dismutase activity, which is always dysregulated due to oxidative stress caused in IBD. The mechanism of antioxidation of probiotics using NRf2-antioxidative response element pathway, nuclear factor-B and protein kinase C pathway may be activated to contribute to the reduction of oxidative-stress-induced IBD. The review focuses on the antioxidative activities of the specific bacterial strains as therapeutic molecules in IBD. Multiple combinations of probiotic strains have still not been adequately studied. We are currently researching the antioxidative effect of Streptococcus thermophilus, Lactobacillus acidophilus and Bifidobacterium bifidumin combination. |
| Publish Date |
2022-08-22 12:18 |
| Citation |
Biswas S, Ray Banerjee E. Probiotic treatment of inflammatory bowel disease: Its extent and intensity. World J Immunol 2022; 12(2): 15-24 |
| URL |
https://www.wjgnet.com/2219-2824/full/v12/i2/15.htm |
| DOI |
https://dx.doi.org/10.5411/wji.v12.i2.15 |
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