Publication Name	World Journal of Clinical Oncology
Manuscript ID	77780
Country	Japan

Received	2022-05-25 04:21
Peer-Review Started	2022-05-25 04:24
First Decision by Editorial Office Director	2022-07-13 09:23
Return for Revision	2022-07-13 09:23
Revised	2022-07-25 08:33
Publication Fee Transferred
Second Decision by Editor	2022-09-05 03:24
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2022-09-06 18:02
Articles in Press	2022-09-06 18:02
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-09-14 06:41
Publish the Manuscript Online	2022-09-22 06:32

ISSN	2218-4333 (online)
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Category	Surgery
Manuscript Type	Observational Study
Article Title	Factors predicting upstaging from clinical N0 to pN2a/N3a in breast cancer patients
Manuscript Source	Unsolicited Manuscript
All Author List	Goshi Oda, Tsuyoshi Nakagawa, Hiroki Mori, Iichiro Onishi, Tomoyuki Fujioka, Mio Mori, Kazunori Kubota, Ryoichi Hanazawa, Akihiro Hirakawa, Toshiaki Ishikawa, Kentaro Okamoto and Hiroyuki Uetake
Funding Agency and Grant Number
Corresponding Author	Goshi Oda, MD, PhD, Assistant Lecturer, Doctor, Doctor, Department of Breast Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 1138519, Japan. odasrg2@tmd.ac.jp
Key Words	Breast cancer; Axillary lymph node metastasis; Positron emission tomography/computed tomography; Sentinel lymph node; Predictive factors of lymphnode metastasis; Standardized uptake value max; Diameter of sentinel lyphonode metastasis
Core Tip	This is the first report to include the results of preoperative positron emission tomography/computed tomography (PET/CT) and to examine results related to the upstaging of pN2a/N3a (more than 4 axillary lymph node metastases) in breast cancer (BC) patients. Specifically, 135 patients who were sentinel lymph node (SLN)-positive and underwent ALN dissection were selected by retrospective chart review, all of whom had BC diagnosed preoperatively as N0 with axillary evaluation by fluorodeoxyglucose (FDG) PET/CT and ultrasound. Our results suggest that the size and number of SLN metastases were still important factors. And, attention should be given to axillary accumulations of FDG, even when faint.
Publish Date	2022-09-22 06:32
Citation	Oda G, Nakagawa T, Mori H, Onishi I, Fujioka T, Mori M, Kubota K, Hanazawa R, Hirakawa A, Ishikawa T, Okamoto K, Uetakesszsz H. Factors predicting upstaging from clinical N0 to pN2a/N3a in breast cancer patients. World J Clin Oncol 2022; 13(9): 748-757
URL	https://www.wjgnet.com/2218-4333/full/v13/i9/748.htm
DOI	https://dx.doi.org/10.5306/wjco.v13.i9.748

Full Article (PDF)	WJCO-13-748.pdf
Full Article (Word)	WJCO-13-748.docx