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8/21/2014 8:53:00 AM | Browse: 543 | Download: 556
Publication Name World Journal of Gastroenterology
Manuscript ID 7797
Country/Territory United Kingdom
Received
2013-11-30 15:10
Peer-Review Started
2013-11-30 21:12
To Make the First Decision
2014-01-09 18:38
Return for Revision
2014-01-20 21:57
Revised
Second Decision
2014-03-19 13:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-03-19 15:25
Articles in Press
2014-05-23 09:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-08-07 13:58
Publish the Manuscript Online
2014-08-20 18:38
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Topic Highlights
Article Title Emerging role of the KRAS-PDK1 axis in pancreatic cancer
Manuscript Source Invited Manuscript
All Author List Riccardo Ferro and Marco Falasca
Funding Agency and Grant Number
Corresponding Author Marco Falasca, Professor, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Blizard Institute, Inositide Signalling Group, 4 Newark Street, London E1 2AT, United Kingdom. m.falasca@qmul.ac.uk
Key Words Pancreatic cancer; Signal transduction; KRAS; Phosphoinositide 3-kinase; 3-phosphoinositide-dependent protein kinase 1
Core Tip Recent evidence suggests that protein kinase 1 (PDK1) is a key oncogenic driver in pancreatic cancer. Furthermore, PDK1 appears to be activated downstream the main pancreatic cancer oncogene KRAS that is mutated in nearly all pancreatic adenocarcinomas. This evidence suggests that PDK1 could represent a novel target in the treatment of pancreatic cancer.
Publish Date 2014-08-20 18:38
Citation Ferro R, Falasca M. Emerging role of the KRAS-PDK1 axis in pancreatic cancer. World J Gastroenterol 2014; 20(31): 10752-10757
URL http://www.wjgnet.com/1007-9327/full/v20/i31/10752.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i31.10752
Full Article (PDF) WJG-20-10752.pdf
Full Article (Word) WJG-20-10752.doc
Manuscript File 7797-Review.docx
Answering Reviewers 7797-Answering reviewers.PDF
Copyright License Agreement 7797-Copyright assignment.PDF
Peer-review Report 7797-Peer review(s).pdf
Scientific Editor Work List 7797-Scientific editor work list.doc