Publication Name	World Journal of Stem Cells
Manuscript ID	79492
Country	China

Received	2022-10-13 11:15
Peer-Review Started	2022-08-24 10:00
To Make the First Decision
Return for Revision	2022-11-14 17:27
Revised	2022-11-23 07:31
Second Decision	2022-12-14 04:08
Accepted by Journal Editor-in-Chief	2022-12-15 18:02
Accepted by Executive Editor-in-Chief	2022-12-23 02:38
Articles in Press	2022-12-23 02:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-01-12 06:20
Publish the Manuscript Online	2023-01-13 10:41

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Acute liver failure: A systematic review and network meta-analysis of optimal type of stem cells in animal models
Manuscript Source	Unsolicited Manuscript
All Author List	Jun-Feng Ma, Jian-Ping Gao and Zi-Wei Shao
Funding Agency and Grant Number
Corresponding Author	Jun-Feng Ma, MD, PhD, Researcher, Department of Surgical Oncology, Gansu Provincial Hospital, No. 204 Donggang West Road, Chengguan District, Lanzhou 730030, Gansu Province, China. majunfeng1992@sina.com
Key Words	Acute liver failure; Stem cells; Animal model; Systematic review; Network meta-analysis
Core Tip	Determination of stem cells with the highest therapeutic potential in acute liver failure is crucial for future animal and clinical research. In this pioneer study, we conducted traditional meta-analysis and network meta-analysis to explore the efficacy of stem cells from four aspects: Alanine aminotransferase, aspartate aminotransferase, tumor necrosis factor-alpha and interleukin-6. We found that although mesenchymal stem cells are the current research hotspot, liver stem cells may have higher therapeutic potential and should be the focus of future research. In addition, we point out the problems existing and the direction of improvement in the future through the quality evaluation.
Publish Date	2023-01-13 10:41
Citation	Ma JF, Gao JP, Shao ZW. Acute liver failure: A systematic review and network meta-analysis of optimal type of stem cells in animal models. World J Stem Cells 2023; 15(1): 1-15
URL	https://www.wjgnet.com/1948-0210/full/v15/i1/1.htm
DOI	https://dx.doi.org/10.4252/wjsc.v15.i1.1

Full Article (PDF)	WJSC-15-1.pdf
Full Article (Word)	WJSC-15-1.docx
PRISMA 2009 Checklist	79492-PRISMA-2009-Checklist-revision.pdf
Manuscript File	79492_Auto_Edited-JLW.docx
Answering Reviewers	79492-Answering reviewers.pdf
Audio Core Tip	79492-Audio core tip.mp3
Biostatistics Review Certificate	79492-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	79492-Conflict-of-interest statement.pdf
Copyright License Agreement	79492-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	79492-Language certificate.pdf
Supplementary Material	79492-Supplementary material.pdf
Peer-review Report	79492-Peer-review(s).pdf
Scientific Misconduct Check	79492-Bing-Wang JJ-2.png
Scientific Editor Work List	79492-Scientific editor work list.pdf
CrossCheck Report	79492-CrossCheck report.pdf