BPG is committed to discovery and dissemination of knowledge
Featured Articles
1/16/2023 6:25:01 AM | Browse: 150 | Download: 471
Publication Name World Journal of Hepatology
Manuscript ID 79531
Country/Territory United Kingdom
Received
2022-08-25 13:52
Peer-Review Started
2022-08-29 01:37
To Make the First Decision
Return for Revision
2022-10-17 03:58
Revised
2022-11-17 08:46
Second Decision
2022-12-30 03:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-01-01 00:51
Articles in Press
2023-01-01 00:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-01-04 01:59
Publish the Manuscript Online
2023-01-16 06:02
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Rising incidence, progression and changing patterns of liver disease in Wales 1999-2019
Manuscript Source Unsolicited Manuscript
All Author List Thomas Peter Ignatius Pembroke, Gareth John, Berry Puyk, Keith Howkins, Ruth Clarke, Fidan Yousuf, Marek Czajkowski, Andrew Godkin, Jane Salmon and Andrew Yeoman
Funding Agency and Grant Number
Corresponding Author Thomas Peter Ignatius Pembroke, FRCP, MBBS, PhD, Doctor, Senior Lecturer, Department of Gastroenterology and Hepatology, University Hospital of Wales, Heath Park, Cardiff CF14 4XN, United Kingdom. thomas.pembroke@wales.nhs.uk
Key Words Epidemiology; Cirrhosis; Liver failure; Non-alcoholic fatty liver disease hepatitis; Hepatocellular carcinoma
Core Tip In this paper we describe the following: (1) Novel methodology for developing a national liver registry; (2) The incidence of liver disease has increased 3.6-fold in Wales between 1999-2019 driven by a 10-fold increase in non-alcoholic fatty liver disease (NAFLD); (3) 3-fold increase in cirrhosis, portal hypertension, decompensation and hepatocellular carcinoma, 2-fold increase in liver disease related mortality between 1999-2019; and (4) Actuarial tables of 10-year liver disease progression: Alcohol-related liver disease, autoimmune liver disease and congestive hepatopathy are associated with increased rates of decompensation and death compared to viral hepatitis and NAFLD. Description of the proportion of patients dying from liver disease as directly, as a contributory cause or where liver disease has not been recording on the death certificate.
Publish Date 2023-01-16 06:02
Citation Pembroke TPI, John G, Puyk B, Howkins K, Clarke R, Yousuf F, Czajkowski M, Godkin A, Salmon J, Yeoman A. Rising incidence, progression and changing patterns of liver disease in Wales 1999-2019. World J Hepatol 2023; 15(1): 89-106
URL https://www.wjgnet.com/1948-5182/full/v15/i1/89.htm
DOI https://dx.doi.org/10.4254/wjh.v15.i1.89
Full Article (PDF) WJH-15-89.pdf
Full Article (Word) WJH-15-89.docx
Manuscript File 79531_Auto_Edited-LM.docx
Answering Reviewers 79531-Answering reviewers.pdf
Audio Core Tip 79531-Audio core tip.m4a
Biostatistics Review Certificate 79531-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 79531-Conflict-of-interest statement.pdf
Copyright License Agreement 79531-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 79531-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 79531-Institutional review board statement.pdf
Supplementary Material 79531-Supplementary material.pdf
Peer-review Report 79531-Peer-review(s).pdf
Scientific Misconduct Check 79531-Bing-Wang JJ-2.png
Scientific Editor Work List 79531-Scientific editor work list.pdf