Publication Name	World Journal of Clinical Infectious Diseases
Manuscript ID	79603
Country	Brazil

Received	2022-08-28 18:37
Peer-Review Started	2022-08-28 18:39
To Make the First Decision
Return for Revision	2022-12-13 02:40
Revised	2022-12-28 20:18
Second Decision	2023-01-31 03:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-02-02 00:42
Articles in Press	2023-02-02 00:42
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-02-12 02:15
Typeset the Manuscript	2023-02-20 09:18
Publish the Manuscript Online	2023-02-27 06:27

ISSN	2220-3176 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Immunology
Manuscript Type	Basic Study
Article Title	Three-dimensional models of antigens with serodiagnosis potential for leprosy: An in silico study
Manuscript Source	Unsolicited Manuscript
All Author List	Bianca Luiza Melo de Assis, Rafaela Viana Vieira, Ian Theodoro Rudenco Gomes Palma, Matheus Bertolini Coutinho, Juliana de Moura, Gabrielle Caroline Peiter and Kádima Nayara Teixeira
Funding Agency and Grant Number
Corresponding Author	Kádima Nayara Teixeira, PhD, Professor, Campus Toledo, Universidade Federal do Paraná, Avenida Max Planck, 3796 , Toledo 85.919-899, Paraná, Brazil. kadimateixeira@ufpr.br
Key Words	Antigens; Leprosy diagnosis; Mycobacterium leprae; Molecular modelling; Serological test; In silico study
Core Tip	Leprosy is a disease with high clinical and epidemiological impact, because it causes irreversible and disfiguring sequelae and has a high incidence in emerging countries. Its variability of manifestations, with different immune responses and the difficulty of cultivating M. leprae in the laboratory, makes it difficult to develop sensitive and specific tests for the diagnosis of the disease, thus emphasizing the importance of in silico studies to help in this problem. In this sense, this study aimed to obtain three-dimensional models of M. leprae antigens, which have stood out in previous studies as candidates for the serological diagnosis of leprosy.
Publish Date	2023-02-27 06:27
Citation	Melo de Assis BL, Viana Vieira R, Rudenco Gomes Palma IT, Bertolini Coutinho M, de Moura J, Peiter GC, Teixeira KN. Three-dimensional models of antigens with serodiagnosis potential for leprosy: An in silico study. World J Clin Infect Dis 2023; 13(1): 1-10
URL	https://www.wjgnet.com/2220-3176/full/v13/i1/1.htm
DOI	https://dx.doi.org/10.5495/wjcid.v13.i1.1

Full Article (PDF)	WJCID-13-1.pdf
Full Article (Word)	WJCID-13-1.docx
Manuscript File	79603_Auto_Edited-Ma JY.docx
Answering Reviewers	79603-Answering reviewers.pdf
Audio Core Tip	79603-Audio core tip.aac
Conflict-of-Interest Disclosure Form	79603-Conflict-of-interest statement.pdf
Copyright License Agreement	79603-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document	79603-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	79603-Language certificate.pdf
Peer-review Report	79603-Peer-review(s).pdf
Scientific Misconduct Check	79603-Bing-Liu JH-2.jpg
Scientific Misconduct Check	79603-CrossCheck.jpg
Scientific Editor Work List	79603-Scientific editor work list.pdf