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1/18/2023 9:50:25 AM | Browse: 345 | Download: 863
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Received |
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2022-09-13 11:40 |
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Peer-Review Started |
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2022-09-13 11:42 |
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To Make the First Decision |
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Return for Revision |
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2022-10-04 05:44 |
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Revised |
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2022-10-15 05:43 |
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Second Decision |
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2022-12-01 03:25 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-01 23:33 |
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Articles in Press |
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2022-12-01 23:33 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-11-24 05:25 |
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Typeset the Manuscript |
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2023-01-12 03:26 |
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Publish the Manuscript Online |
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2023-01-18 03:45 |
ISSN |
2220-3249 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Systematic Reviews |
Article Title |
COVID-19-related liver injury: Focus on genetic and drug-induced perspectives
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Manuscript Source |
Invited Manuscript |
All Author List |
Deepak Parchwani, Amit D Sonagra, Sagar Dholariya, Anita Motiani and Ragini Singh |
Funding Agency and Grant Number |
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Corresponding Author |
Sagar Dholariya, MD, Assistant Professor, Department of Biochemistry, All India Institute of Medical Sciences, Jamnagar Road, Khandheri, Rajkot 360001, India. drsagar.dholariya@gmail.com |
Key Words |
SARS-CoV-2; Liver injury; Genetic prospective; Drug-induced liver injury; Prognosis; COVID-19 |
Core Tip |
Evidence highlights the multisystemic nature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Hepatic dysfunction is the primary extrapulmonary manifestation. In addition to the direct cytopathic effect of the virus, iatrogenic causes and genetic susceptibility are also postulated in the pathogenesis of hepatic damage in SARS-CoV-2 infection. Degree of liver toxicity in terms of altered biochemical indices were consistent with severity of coronavirus disease 2019 (COVID-19) illness and hospital stay. Hence, serial monitoring of hepatic indices in COVID-19 hospitalized patients may provide useful prognostic value to make timely corrective actions to avoid clinical deterioration. |
Publish Date |
2023-01-18 03:45 |
Citation |
Parchwani D, Sonagra AD, Dholariya S, Motiani A, Singh R. COVID-19-related liver injury: Focus on genetic and drug-induced perspectives. World J Virol 2023; 12(1): 53-67 |
URL |
https://www.wjgnet.com/2220-3249/full/v12/i1/53.htm |
DOI |
https://dx.doi.org/10.5501/wjv.v12.i1.53 |
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