Publication Name	World Journal of Gastroenterology
Manuscript ID	80425
Country	Australia

Received	2022-09-28 11:08
Peer-Review Started	2022-09-27 11:06
To Make the First Decision
Return for Revision	2022-10-17 22:39
Revised	2022-11-01 05:45
Second Decision	2022-12-20 08:13
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-12-21 03:26
Articles in Press	2022-12-21 03:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-12-30 05:59
Publish the Manuscript Online	2023-01-06 02:52

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Opinion Review
Article Title	Acute-on-chronic liver failure: Controversies and consensus
Manuscript Source	Invited Manuscript
All Author List	Natalie L Y Ngu, Eliza Flanagan, Sally Bell and Suong T Le
Funding Agency and Grant Number
Corresponding Author	Natalie L Y Ngu, MBBS, Doctor, Doctor, Department of Gastroenterology and Hepatology, Monash Health, Level 3, 246 Clayton Road, Clayton 3168, Victoria, Australia. natalie.ngu@monash.edu
Key Words	Acute-on-chronic liver failure; Liver cirrhosis; End stage liver disease; Epidemiology; Mortality
Core Tip	Acute-on-chronic liver failure is characterised by rapid clinical deterioration in patients with chronic liver disease. Consequences include high short-term morbidity, mortality, and healthcare resource use. Heterogenous definitions, diagnostic criteria, and treatment guidelines create further challenges to optimal care. This review summarises epidemiology and resource utilisation, key clinical features, strategies for management, and research gaps.
Publish Date	2023-01-06 02:52
Citation	Ngu NLY, Flanagan E, Bell S, Le ST. Acute-on-chronic liver failure: Controversies and consensus. World J Gastroenterol 2023; 29(2): 232-240
URL	https://www.wjgnet.com/1007-9327/full/v29/i2/232.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i2.232

Full Article (PDF)	WJG-29-232.pdf
Full Article (Word)	WJG-29-232.docx
Manuscript File	80425_Auto_Edited-JLW.docx
Answering Reviewers	80425-Answering reviewers.pdf
Audio Core Tip	80425-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	80425-Conflict-of-interest statement.pdf
Copyright License Agreement	80425-Copyright license agreement.pdf
Peer-review Report	80425-Peer-review(s).pdf
Scientific Misconduct Check	80425-Bing-Chen YL-2.png
Scientific Editor Work List	80425-Scientific editor work list.pdf
CrossCheck Report	80425-CrossCheck report.pdf