BPG is committed to discovery and dissemination of knowledge
Featured Articles
4/13/2023 8:23:28 AM | Browse: 181 | Download: 646
 |
Received |
|
2022-09-28 12:04 |
|
Peer-Review Started |
|
2022-09-28 12:09 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2022-10-17 22:28 |
|
Revised |
|
2022-10-23 19:28 |
|
Second Decision |
|
2023-03-21 03:09 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2023-03-21 06:41 |
|
Articles in Press |
|
2023-03-21 06:41 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2023-02-27 03:20 |
|
Typeset the Manuscript |
|
2023-03-27 07:59 |
|
Publish the Manuscript Online |
|
2023-04-13 08:14 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Insight into the liver dysfunction in COVID-19 patients: Molecular mechanisms and possible therapeutic strategies
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Naina Khullar, Jasvinder Singh Bhatti, Satwinder Singh, Bhawana Thukral, P Hemachandra Reddy and Gurjit Kaur Bhatti |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Engineering Research Board India grant |
TAR/2020/000430, EEQ/2020/000188 |
| Indian Council of Medical Research grant |
BMI/12(08)/2021-6329 |
|
| Corresponding Author |
Gurjit Kaur Bhatti, BSc, MSc, PhD, Associate Professor, Department of Medical Lab Technology, University Institute of Applied Health Sciences, Chandigarh University, Gharuan, Mohali 140413, Punjab, India. bhattigk@yahoo.com |
| Key Words |
COVID-19; Liver damage; Pharmacotherapy; Cytokine storm; Molecular mechanisms |
| Core Tip |
Several review articles have contributed to the pathophysiology, therapeutic strategies, vaccine development, and clinical trials of coronavirus disease 2019 (COVID-19). Since the liver is the primary site of immune protein synthesis, any liver defect may compromise the immune system. Patients with chronic liver disease are at a higher risk of severe COVID-19. This review article demonstrated the pathophysiology and molecular mechanisms responsible for more severe outcomes in patients with hepatic defects. Further, we critically evaluated the molecular mechanisms concerning hepatotropism in patients with COVID-19, which could lead to the development of new therapeutics. |
| Publish Date |
2023-04-13 08:14 |
| Citation |
Khullar N, Bhatti JS, Singh S, Thukral B, Reddy PH, Bhatti GK. Insight into the liver dysfunction in COVID-19 patients: Molecular mechanisms and possible therapeutic strategies. World J Gastroenterol 2023; 29(14): 2064-2077 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i14/2064.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i14.2064 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
