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2/6/2023 7:31:04 AM | Browse: 135 | Download: 272
Publication Name World Journal of Clinical Cases
Manuscript ID 80785
Country/Territory China
Received
2022-10-12 14:44
Peer-Review Started
2022-10-12 14:45
To Make the First Decision
Return for Revision
2022-12-13 03:28
Revised
2022-12-13 07:23
Second Decision
2022-12-30 03:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-01-03 00:53
Articles in Press
2023-01-03 00:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-01-28 06:26
Publish the Manuscript Online
2023-02-06 06:38
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Clinical and Translational Research
Article Title CD93 serves as a potential biomarker of gastric cancer and correlates with the tumor microenvironment
Manuscript Source Unsolicited Manuscript
All Author List Zheng Li, Xiao-Jie Zhang, Chong-Yuan Sun, He Fei, Ze-Feng Li and Dong-Bing Zhao
Funding Agency and Grant Number
Corresponding Author Dong-Bing Zhao, MD, Professor, Department of Pancreatic and Gastric Surgical Oncology, National Cancer Center/National Clinical Research for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.17 Pan-jia-yuan South Lane, Chaoyang District, Beijing 100021, China. dbzhao@cicams.ac.cn
Key Words Gastric cancer; CD93; Tumor microenvironment; Immunotherapy; Prognosis; Biomarker
Core Tip Gastric cancer (GC) is an aggressive malignancy, with a 5-year survival rate lower than 20%. The disease burden caused by GC remains heavy worldwide. In this study, various analyses were performed using transcriptomic profiles from the Gene Expression Omnibus databases and The Cancer Genome Atlas. Finally, enrichment analysis and protein-protein interaction network were constructed. CD93 is identified as a diagnostic and prognostic biomarker of GC, which is closely related to the immune infiltration in the tumor microenvironment. Then, Immune-related gene modules were identified to further reveal the relationship between CD93 and immune characteristics.
Publish Date 2023-02-06 06:38
Citation Li Z, Zhang XJ, Sun CY, Fei H, Li ZF, Zhao DB. CD93 serves as a potential biomarker of gastric cancer and correlates with the tumor microenvironment. World J Clin Cases 2023; 11(4): 738-755
URL https://www.wjgnet.com/2307-8960/full/v11/i4/738.htm
DOI https://dx.doi.org/10.12998/wjcc.v11.i4.738
Full Article (PDF) WJCC-11-738.pdf
Full Article (Word) WJCC-11-738.docx
Manuscript File 80785_Auto_Edited-JLW.docx
Answering Reviewers 80785-Answering reviewers.pdf
Audio Core Tip 80785-Audio core tip.m4a
Biostatistics Review Certificate 80785-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 80785-Conflict-of-interest statement.pdf
Copyright License Agreement 80785-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 80785-Language certifficate.pdf
Peer-review Report 80785-Peer-review(s).pdf
Scientific Editor Work List 80785-Scientific editor work list.pdf