Publication Name	World Journal of Cardiology
Manuscript ID	80881
Country	India

Received	2022-10-18 17:01
Peer-Review Started	2022-10-18 17:04
To Make the First Decision
Return for Revision	2022-11-02 03:17
Revised	2022-11-08 18:44
Second Decision	2022-12-22 03:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-12-23 02:44
Articles in Press	2022-12-23 02:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-12-27 06:23
Publish the Manuscript Online	2023-01-12 04:00

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Observational Study
Article Title	Role of fibrinogen, albumin and fibrinogen to albumin ratio in determining angiographic severity and outcomes in acute coronary syndrome
Manuscript Source	Invited Manuscript
All Author List	Kunaal Makkar, Yash Paul Sharma, Akash Batta, Juniali Hatwal and Prashant Kumar Panda
Funding Agency and Grant Number
Corresponding Author	Akash Batta, Doctor, FACC, MBBS, MD, Assistant Professor, Department of Cardiology, Dayanand Medical College and Hospital, Civil Lines, Tagore Nagar, Ludhiana 141001, Punjab, India. akashbatta02@gmail.com
Key Words	Acute coronary syndrome; Albumin; Fibrinogen; Fibrinogen to albumin ratio; Total occlusion of culprit artery
Core Tip	The study highlights the role of cost-effective, readily available biomarkers fibrinogen and albumin in predicting angiographic severity and clinical outcomes in patients with acute coronary syndrome. Fibrinogen to albumin ratio independently predicted outcomes with greater accuracy compared to fibrinogen or albumin alone. Fibrinogen albumin ratio (FAR) ≥ 19.2, had a sensitivity of 76.9% and specificity of 78.9 % to predict ≤ thrombolysis in myocardial infarction 1 flow in culprit artery in ST elevation myocardial infarction (STEMI) patients. Even in non-STEMI patients, FAR ≥ 18.85 predicted the same with 80% sensitivity and 63% specificity.
Publish Date	2023-01-12 04:00
Citation	Makkar K, Sharma YP, Batta A, Hatwal J, Panda PK. Role of fibrinogen, albumin and fibrinogen to albumin ratio in determining angiographic severity and outcomes in acute coronary syndrome. World J Cardiol 2023; 15(1): 13-22
URL	https://www.wjgnet.com/1949-8462/full/v15/i1/13.htm
DOI	https://dx.doi.org/10.4330/wjc.v15.i1.13

Full Article (PDF)	WJC-15-13.pdf
Full Article (Word)	WJC-15-13.docx
Manuscript File	80881_Auto_Edited-JLW.docx
Answering Reviewers	80881-Answering reviewers.pdf
Audio Core Tip	80881-Audio core tip.mp3
Biostatistics Review Certificate	80881-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	80881-Conflict-of-interest statement.pdf
Copyright License Agreement	80881-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	80881-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	80881-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	80881-Language certificate.pdf
Peer-review Report	80881-Peer-review(s).pdf
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Scientific Editor Work List	80881-Scientific editor work list.pdf