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1/5/2023 7:15:38 AM | Browse: 165 | Download: 666
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Received |
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2022-10-23 06:56 |
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Peer-Review Started |
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2022-10-23 06:59 |
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To Make the First Decision |
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Return for Revision |
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2022-11-25 02:18 |
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Revised |
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2022-12-14 13:39 |
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Second Decision |
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2022-12-23 03:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-23 08:47 |
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Articles in Press |
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2022-12-23 08:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-12-26 05:34 |
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Publish the Manuscript Online |
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2023-01-05 03:12 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Minireviews |
| Article Title |
Role of the extracellular matrix in COVID-19
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jia-Jia Huang, Chu-Wen Wang, Ying Liu, Ying-Ying Zhang, Nai-Bin Yang, Yu-Chun Yu, Qi Jiang, Qi-Fa Song and Guo-Qing Qian |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Key Program of the Natural Science Foundation of Ningbo |
202003N4019 |
| Ningbo City COVID-19 Epidemic Prevention and Control Project |
202002N7033 |
| Zhejiang Medical and Health Science and Technology Project |
2019KY154 |
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| Corresponding Author |
Guo-Qing Qian, MD, PhD, Associate Chief Physician, Department of Infectious Diseases, Ningbo First Hospital, No. 59 Liuting Road, Ningbo 315000, Zhejiang Province, China. bill.qian@outlook.com |
| Key Words |
COVID-19; SARS-CoV-2; Extracellular Matrix; Inflammation |
| Core Tip |
Coronavirus disease 2019 (COVID-19) shows abnormal expression of the extracellular matrix (ECM). The ECM is a type of macromolecular network secreted by cells into the extracellular stroma, which is also the major component of connective tissue. It can trigger various activities biologically essential for tissue homeostasis and normal organ development. Upon severe acute respiratory syndrome coronavirus 2 infection, ECM proteins are involved in the recruitment of inflammatory cells and interference with target organ metabolism, including that of the lung. The manuscript addresses the current findings of ECM, which are linked to the severity and inflammation of COVID-19, and the roles of ECM in COVID-19. |
| Publish Date |
2023-01-05 03:12 |
| Citation |
Huang JJ, Wang CW, Liu Y, Zhang YY, Yang NB, Yu YC, Jiang Q, Song QF, Qian GQ. Role of the extracellular matrix in COVID-19. World J Clin Cases 2023; 11(1): 73-83 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i1/73.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i1.73 |
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