Publication Name	World Journal of Clinical Cases
Manuscript ID	81054
Country	United States

Received	2022-10-22 23:11
Peer-Review Started	2022-10-22 23:13
First Decision by Editorial Office Director	2022-12-26 08:29
Return for Revision	2022-12-28 01:47
Revised	2023-01-08 15:44
Publication Fee Transferred
Second Decision by Editor	2023-02-17 03:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2023-02-17 07:38
Articles in Press	2023-02-17 07:38
Edit the Manuscript by Language Editor	2023-02-15 01:42
Typeset the Manuscript	2023-02-20 06:52
Publish the Manuscript Online	2023-03-07 08:12

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Medicine, General & Internal
Manuscript Type	Minireviews
Article Title	Diabetic foot ulcer: A comprehensive review of pathophysiology and management modalities
Manuscript Source	Invited Manuscript
All Author List	Joel M Raja, Miguel A Maturana, Sharif Kayali, Amir Khouzam and Nephertiti Efeovbokhan
Funding Agency and Grant Number
Corresponding Author	Joel M Raja, MD, Postdoctoral Fellow, Department of Internal Medicine, University of Tennessee Health Science Center, 2750 Mcvay Road, Memphis, Memphis, TN 38119, United States. jraja@uthsc.edu
Key Words	Diabetes; Ulcer; Foot; Antibiotics; Revascularization; Cell therapy
Core Tip	Diabetic foot ulcer: Pathophysiology: - Neuropathy including sensory and motor - Vascular insufficiency leading to ischemia - Secondary infection with inflammation. Overview of management: (1) Preventive care including self-screening, health care screening, insoles, podiatric care; (2) Noninvasive modalities including wound dressing, human skin equivalent, topical growth factors, shock wave therapy, stem cell therapy, hyperbaric oxygen, negative pressure, shock wave therapy, maggot therapy, antibiotics; and (3) Invasive modalities including debridement, revascularization, skin grafting, amputation.
Publish Date	2023-03-07 08:12
Citation	Raja JM, Maturana MA, Kayali S, Khouzam A, Efeovbokhan N. Diabetic foot ulcer: A comprehensive review of pathophysiology and management modalities. World J Clin Cases 2023; 11(8): 1684-1693
URL	https://www.wjgnet.com/2307-8960/full/v11/i8/1684.htm
DOI	https://dx.doi.org/10.12998/wjcc.v11.i8.1684

Full Article (PDF)	WJCC-11-1684.pdf
Full Article (Word)	WJCC-11-1684.docx
Manuscript File	81054_Auto_Edited-DMW-Filipodia-JLW.docx
Answering Reviewers	81054-Answering reviewers.pdf
Audio Core Tip	81054-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	81054-Conflict-of-interest statement.pdf
Copyright License Agreement	81054-Copyright license agreement.pdf
Peer-review Report	81054-Peer-review(s).pdf
Scientific Misconduct Check	81054-Bing-Wang DM-1.png
Scientific Misconduct Check	81054-CrossCheck.png
Scientific Editor Work List	81054-Scientific editor work list.pdf
CrossCheck Report	81054-CrossCheck report.pdf