Publication Name	World Journal of Hepatology
Manuscript ID	81125
Country	China

Received	2022-10-26 12:24
Peer-Review Started	2022-10-26 12:26
To Make the First Decision
Return for Revision	2022-11-28 10:33
Revised	2023-02-14 13:12
Second Decision	2023-03-28 03:30
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-03-29 08:04
Articles in Press	2023-03-29 08:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-04-17 01:42
Publish the Manuscript Online	2023-04-20 07:26

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Ablative strategies for recurrent hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Lin Wang, Bao-Xian Liu and Hai-Yi Long
Funding Agency and Grant Number
Corresponding Author	Hai-Yi Long, MD, Doctor, Doctor, Department of Medical Ultrasound, Institute of Diagnostic and Interventional Ultrasound, the First Affiliated Hospital of SunYat-sen University, No. 58 Zhongshan Road 2, Guangzhou 510080, Guangdong Province, China. longhy9@mail.sysu.edu.cn
Key Words	Hepatocellular carcinoma; Recurrence; Ablative therapy; Thermal ablation
Core Tip	Despite the tremendous efforts in the fight against hepatocellular carcinoma, there is still no way to prevent its recurrence. Intrahepatic recurrence can be treated by repeated resection and ablation, and there are many studies showing the advantages and disadvantages of each treatment method. For tumors ≤ 3 cm in diameter, there is no significant difference between surgery resection and radiofrequency/microwave ablation treatment. Non-thermal ablation treatment has clearer borders but a higher postoperative recurrence rate. Percutaneous ethanol injection has comparable efficacy to radiofrequency ablation for small tumors. Multiple recurrences require combined systemic therapy.
Publish Date	2023-04-20 07:26
Citation	Wang L, Liu BX, Long HY. Ablative strategies for recurrent hepatocellular carcinoma. World J Hepatol 2023; 15(4): 515-524
URL	https://www.wjgnet.com/1948-5182/full/v15/i4/515.htm
DOI	https://dx.doi.org/10.4254/wjh.v15.i4.515

Full Article (PDF)	WJH-15-515-with-cover.pdf
Full Article (Word)	WJH-15-515.docx
Manuscript File	81125_Auto_Edited-JLW.docx
Answering Reviewers	81125-Answering reviewers.pdf
Audio Core Tip	81125-Audio core tip.wav
Conflict-of-Interest Disclosure Form	81125-Conflict-of-interest statement.pdf
Copyright License Agreement	81125-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	81125-Language certificate.pdf
Peer-review Report	81125-Peer-review(s).pdf
Scientific Misconduct Check	81125-Bing-Li L-2.png
Scientific Editor Work List	81125-Scientific editor work list.pdf
CrossCheck Report	81125-CrossCheck report.pdf
CrossCheck Report	81125-CrossCheck.png