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2/21/2023 6:42:14 AM | Browse: 240 | Download: 974
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Received |
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2022-10-27 11:58 |
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Peer-Review Started |
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2022-10-27 12:00 |
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To Make the First Decision |
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Return for Revision |
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2022-11-14 08:44 |
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Revised |
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2022-11-19 13:10 |
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Second Decision |
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2022-12-20 08:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-21 07:25 |
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Articles in Press |
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2022-12-21 07:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-12-26 01:58 |
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Publish the Manuscript Online |
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2023-02-21 06:19 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Comparison of genomic and transcriptional microbiome analysis in gastric cancer patients and healthy individuals
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Darja Nikitina, Konrad Lehr, Ramiro Vilchez-Vargas, Laimas Virginijus Jonaitis, Mindaugas Urba, Juozas Kupcinskas, Jurgita Skieceviciene and Alexander Link |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| European Social Fund |
09.3.3-LMT-K-712-01 0130 |
| “Autonomy in old Age” research group |
ZS/2018/11/95324 |
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| Corresponding Author |
Jurgita Skieceviciene, PhD, Professor, Senior Researcher, Institute for Digestive Research, Lithuanian University of Health Sciences, Eivenių g. 4, Kaunas 44307, Lithuania. jurgita.skieceviciene@lsmu.lt |
| Key Words |
Gastric cancer; Microbiome; Helicobacter pylori; 16S rRNA gene; 16S rRNA transcript; 16S rDNA |
| Core Tip |
In this study, we aimed to characterize the microbiota of gastric cancer (GC) on two levels: 16S rRNA gene and its transcript. Our study showed that only a small portion of bacterial sequences overlapped using those two approaches. Moreover, our study revealed that obtained results comparing the case group with the controls depend on the chosen modality. We also showed that Reyranella and Sediminibacterium was associated with the Lauren classification and RNA level was more sensitive to detect low abundant bacteria. This study provides novel insights into microbiome study as well as new founding related to complex GC pathogenesis. |
| Publish Date |
2023-02-21 06:19 |
| Citation |
Nikitina D, Lehr K, Vilchez-Vargas R, Jonaitis LV, Urba M, Kupcinskas J, Skieceviciene J, Link A. Comparison of genomic and transcriptional microbiome analysis in gastric cancer patients and healthy individuals. World J Gastroenterol 2022; 29(7): 1202-1218 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i7/1202.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i7.1202 |
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