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2/14/2023 8:40:46 AM | Browse: 243 | Download: 612
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Received |
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2022-11-04 10:35 |
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Peer-Review Started |
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2022-11-04 10:36 |
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To Make the First Decision |
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Return for Revision |
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2022-12-13 08:53 |
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Revised |
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2022-12-25 14:21 |
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Second Decision |
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2023-01-20 03:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-01-20 06:05 |
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Articles in Press |
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2023-01-20 06:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-02-03 07:55 |
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Publish the Manuscript Online |
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2023-02-14 07:03 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Case Report |
| Article Title |
Bladder preservation in complicated invasive urothelial carcinoma following treatment with cisplatin/gemcitabine plus tislelizumab: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rui Yang, Jun-Xing Chen, Shu-Hang Luo, Ting-Ting Chen, Ling-Wu Chen and Bin Huang |
| Funding Agency and Grant Number |
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| Corresponding Author |
Bin Huang, MD, PhD, Doctor, Doctor, Department of Urology, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhong Shan 2nd Road, Guangzhou 510080, Guangdong Province, China. huangb48@mail.sysu.edu.cn |
| Key Words |
Invasive urothelial carcinoma; Immunotherapy; Chemotherapy; Squamous and glandular differentiation; Tislelizumab; Case report |
| Core Tip |
Urothelial carcinoma (UC) with complicated differentiation is highly malignant, and radical cystectomy (RC) is the preferred treatment. Because of the complications related to RC, bladder-sparing therapy has become a research hotspot. We here report a patient who was diagnosed with muscle-invasive bladder cancer with squamous and glandular differentiation and positive programmed cell death-ligand 1 (PD-L1) expression. The patient received a combination of chemotherapy and immunotherapy and achieved bladder preservation and has maintained tumor-free for over two years. This case highlights that the combination treatment might be an effective and safe strategy for UC with divergent histologic differentiation and positive PD-L1 expression. |
| Publish Date |
2023-02-14 07:03 |
| Citation |
Yang R, Chen JX, Luo SH, Chen TT, Chen LW, Huang B. Bladder preservation in complicated invasive urothelial carcinoma following treatment with cisplatin/gemcitabine plus tislelizumab: A case report. World J Clin Cases 2023; 11(5): 1165-1174 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i5/1165.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i5.1165 |
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