Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	81592
Country	India

Received	2022-11-16 13:04
Peer-Review Started	2022-11-16 13:07
To Make the First Decision
Return for Revision	2022-12-12 07:21
Revised	2022-12-25 17:15
Second Decision	2023-01-13 03:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-01-17 18:21
Articles in Press	2023-01-17 18:21
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-01-10 19:14
Typeset the Manuscript	2023-01-19 04:13
Publish the Manuscript Online	2023-01-20 07:24

ISSN	2150-5330 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Growth hormone and gastrointestinal malignancy: An intriguing link
Manuscript Source	Invited Manuscript
All Author List	Rajan Palui, Kalyani Sridharan, Sadishkumar Kamalanathan, Jayaprakash Sahoo and Dukhabandhu Naik
Funding Agency and Grant Number
Corresponding Author	Jayaprakash Sahoo, MBBS, MD, Additional Professor, Department of Endocrinology, Jawaharlal Institute of Postgraduate Medical Education and Research, Room 5444, Fourth Floor, Super specialty Block, D. Nagar, Puducherry 605006, India. jppgi@yahoo.com
Key Words	Acromegaly; Colonoscopy; Colorectal carcinoma; Recombinant growth hormone
Core Tip	Growth hormone (GH) excess is associated with systemic complications including an increased risk of gastrointestinal (GI) neoplasms. Although most studies show an increased incidence of all GI neoplasms, most evidence is for increased colorectal adenomas and carcinomas. However, recent studies show similar colon cancer-specific mortality rates in acromegaly as compared to the general population. Screening guidelines for acromegaly recommend an initial colonoscopy in all patients with further follow-up recommended for patients with high risk. Most cohort studies do not report any increased risk of GI neoplasms for patients on recombinant GH therapy.
Publish Date	2023-01-20 07:24
Citation	Palui R, Sridharan K, Kamalanathan S, Sahoo J, Naik D. Growth hormone and gastrointestinal malignancy: An intriguing link. World J Gastrointest Pathophysiol 2023; 14(1): 1-11
URL	https://www.wjgnet.com/2150-5330/full/v14/i1/1.htm
DOI	https://dx.doi.org/10.4291/wjgp.v14.i1.1

Full Article (PDF)	WJGP-14-1.pdf
Full Article (Word)	WJGP-14-1.docx
Manuscript File	81592_Auto_Edited-LM.docx
Answering Reviewers	81592-Answering reviewers.pdf
Audio Core Tip	81592-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	81592-Conflict-of-interest statement.pdf
Copyright License Agreement	81592-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	81592-Language certificate.pdf
Peer-review Report	81592-Peer-review(s).pdf
Scientific Misconduct Check	81592-Bing-Wang LL-2.png
Scientific Editor Work List	81592-Scientific editor work list.pdf
CrossCheck Report	81592-CrossCheck report.pdf