Publication Name	World Journal of Gastroenterology
Manuscript ID	82008
Country	Italy

Received	2022-12-01 14:45
Peer-Review Started	2022-12-01 14:48
To Make the First Decision
Return for Revision	2023-02-01 23:04
Revised	2023-02-02 10:16
Second Decision	2023-02-27 03:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-03-07 18:15
Articles in Press	2023-03-07 18:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-03-13 04:48
Publish the Manuscript Online	2023-03-17 06:20

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Factors affecting the quality of bowel preparation for colonoscopy in hard-to-prepare patients: Evidence from the literature
Manuscript Source	Invited Manuscript
All Author List	Endrit Shahini, Emanuele Sinagra, Alessandro Vitello, Rocco Ranaldo, Antonella Contaldo, Antonio Facciorusso and Marcello Maida
Funding Agency and Grant Number
Corresponding Author	Endrit Shahini, MD, Doctor, Doctor, Research Fellow, Gastroenterology Unit, National Institute of Gastroenterology-IRCCS “Saverio de Bellis”, Castellana Grotte, 27 Via Turi, Bari 70013, Italy. endrit.shahini@irccsdebellis.it
Key Words	Colorectal cancer; Colonoscopy; Adenoma detection rate; Bowel preparation; Polyethylene glycol
Core Tip	Almost a quarter of procedures are still performed with inadequate preparation. A strategy that includes a low-fiber diet for an extended period of time, a split preparation regimen, and a colonoscopy within 5 h of the end of preparation may improve cleansing success rates in the elderly. In addition, while no specific product is recommended for difficult-to-prepare patients, clinical evidence suggests that 1-L polyethylene glycol (PEG) plus ascorbic acid preparation is associated with higher cleansing success in hospitalized and inflammatory bowel disease patients. Isotonic high volume PEG solutions should be given to patients with severe renal failure.
Publish Date	2023-03-17 06:20
Citation	Shahini E, Sinagra E, Vitello A, Ranaldo R, Contaldo A, Facciorusso A, Maida M. Factors affecting the quality of bowel preparation for colonoscopy in hard-to-prepare patients: Evidence from the literature. World J Gastroenterol 2023; 29(11): 1685-1707
URL	https://www.wjgnet.com/1007-9327/full/v29/i11/1685.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i11.1685

Full Article (PDF)	WJG-29-1685.pdf
Full Article (Word)	WJG-29-1685.docx
Manuscript File	82008_Auto_Edited-LM.docx
Answering Reviewers	82008-Answering reviewers.pdf
Audio Core Tip	82008-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	82008-Conflict-of-interest statement.pdf
Copyright License Agreement	82008-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	82008-Language certificate.pdf
Supplementary Material	82008-Supplementary material.pdf
Peer-review Report	82008-Peer-review(s).pdf
Scientific Misconduct Check	82008-Bing-Chen YL-2.jpg
Scientific Editor Work List	82008-Scientific editor work list.pdf
CrossCheck Report	82008-CrossCheck report.pdf