ISSN |
2220-3230 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
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For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Transplantation |
Manuscript Type |
Retrospective Study |
Article Title |
Long-term outcomes of paediatric liver transplantation in acute liver failure vs end-stage chronic liver disease: Retrospective observational study
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Amr M Alnagar, Abdul R Hakeem, Khaled Daradka, Eirini Kyrana, Marumbo Methga, Karthikeyan Palaniswamy, Sanjay Rajwal, Jamila Mulla, Moira O'meara, Vivek Upasani, Dhakshinamoorthy Vijayanand, Raj Prasad and Magdy S Attia |
Funding Agency and Grant Number |
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Corresponding Author |
Abdul R Hakeem, FEBS, FRCS, PhD, N/A, N/A, Liver and Transplant Surgery, The Leeds Teaching Hospitals, NHS Foundation Trust, Leeds City Centre-Beckett Street, Leeds LS9 7TF, United Kingdom. abdul.hakeem1@nhs.net |
Key Words |
Paediatric liver transplantation; Acute liver failure; End-stage chronic liver disease; Graft failure; Patient survival; Complications |
Core Tip |
To our experience, this research is the first to compare the complications and survival outcomes in acute liver failure (ALF) and end-stage chronic liver disease (ESCLD) children post-paediatric liver transplantation (PLT). This study has not only shown that survival in the ALF group is significantly inferior post-PLT but also showed a different pattern of survival where ALF survival is mostly affected in the first year post-transplant and then stabilizes, while ESCLD survival declines steadily over time. |
Publish Date |
2023-03-17 06:08 |
Citation |
Alnagar AM, Hakeem AR, Daradka K, Kyrana E, Methga M, Palaniswamy K, Rajwal S, Mulla J, O'meara M, Upasani V, Vijayanand D, Prasad R, Attia MS. Long-term outcomes of paediatric liver transplantation in acute liver failure vs end-stage chronic liver disease: Retrospective observational study. World J Transplant 2023; 13(3): 96-106 |
URL |
https://www.wjgnet.com/2220-3230/full/v13/i3/96.htm |
DOI |
https://dx.doi.org/10.5500/wjt.v13.i3.96 |