Publication Name	World Journal of Gastroenterology
Manuscript ID	82122
Country	United Kingdom

Received	2022-12-06 22:34
Peer-Review Started	2022-12-06 22:36
To Make the First Decision
Return for Revision	2023-02-01 22:58
Revised	2023-02-10 02:23
Second Decision	2023-03-21 03:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-03-21 06:54
Articles in Press	2023-03-21 06:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-03-26 15:21
Publish the Manuscript Online	2023-04-07 05:51

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Minireviews
Article Title	Liver transplantation in the management of cholangiocarcinoma: Evolution and contemporary advances
Manuscript Source	Invited Manuscript
All Author List	Aditya Borakati, Farid Froghi, Ricky H Bhogal and Vasileios K Mavroeidis
Funding Agency and Grant Number
Corresponding Author	Vasileios K Mavroeidis, FACS, FICS, FRCS, MD, MSc, Surgeon, Department of Academic Surgery, The Royal Marsden NHS Foundation Trust, 203 Fulham Road, London SW3 6JJ, United Kingdom. vasileios.mavroeidis@nhs.net
Key Words	Cholangiocarcinoma; Klatskin tumor; Liver transplantation; Liver cancer; Liver resection; Neoadjuvant therapy
Core Tip	Cholangiocarcinoma (CCA) is an aggressive malignancy with poor prognosis. Radical surgical resection with clear margins may offer a chance of cure but is frequently not possible due to locally advanced disease. In the last two decades, within specific criteria, a protocolised combination of neoadjuvant chemoradiation and orthotopic liver transplantation (LT) has produced excellent results in patients with perihilar CCA, while favourable results have been shown with LT in early intrahepatic CCA in recent years. We review the history and contemporary advances of LT in CCA and discuss future perspectives.
Publish Date	2023-04-07 05:51
Citation	Borakati A, Froghi F, Bhogal RH, Mavroeidis VK. Liver transplantation in the management of cholangiocarcinoma: Evolution and contemporary advances. World J Gastroenterol 2023; 29(13): 1969-1981
URL	https://www.wjgnet.com/1007-9327/full/v29/i13/1969.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i13.1969

Full Article (PDF)	WJG-29-1969.pdf
Full Article (Word)	WJG-29-1969.docx
Manuscript File	82122_Auto_Edited-JLW.docx
Answering Reviewers	82122-Answering reviewers.pdf
Audio Core Tip	82122-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	82122-Conflict-of-interest statement.pdf
Copyright License Agreement	82122-Copyright license agreement.pdf
Supplementary Material	82122-Copyright permission.pdf
Peer-review Report	82122-Peer-review(s).pdf
Scientific Misconduct Check	82122-Bing-Li L-2.png
Scientific Editor Work List	82122-Scientific editor work list.pdf