BPG is committed to discovery and dissemination of knowledge
Featured Articles
5/25/2023 4:17:24 PM | Browse: 163 | Download: 192
Publication Name World Journal of Clinical Cases
Manuscript ID 82368
Country China
2022-12-16 11:57
Peer-Review Started
2022-12-16 11:59
To Make the First Decision
Return for Revision
2023-02-28 08:37
2023-03-08 07:50
Second Decision
2023-04-11 03:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-04-12 01:40
Articles in Press
2023-04-12 01:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-05-06 01:44
Publish the Manuscript Online
2023-05-25 16:10
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Clinical and Translational Research
Article Title Establishment of a prognostic model related to tregs and natural killer cells infiltration in bladder cancer
Manuscript Source Unsolicited Manuscript
All Author List Yan-Jie Yang, Xiao-Qing Xu, Yi-Chao Zhang, Peng-Cheng Hu and Wu-Xia Yang
Funding Agency and Grant Number
Corresponding Author Wu-Xia Yang, The Graduate School/Department of Traditional Chinese Medicine, Tianjin Medical University/Tianjin Medical University General Hospital, Tianjin 300041, China. yangwuxia_09@tmu.edu.cn
Key Words Natural killer cells; Tregs; Bladder cancer; Weighted gene coexpression network analysis; Bladder cancer Treatment; Immunotherapy; Computational molecular biology
Core Tip Tregs are thought to be connected to tumor cells evading the immune system, which is linked to cancer patients' poor prognoses. Natural killer (NK) cells control different immune responses and show antitumor cytotoxicity without being previously sensitized. We determined the immunological scores of several cell types in Bladder urothelial carcinoma, discovered a gene set that was favorably connected with the Tregs score and negatively correlated with the NK cells score, and built a model that was related to prognosis. The model can predict the sensitivity of patients to chemotherapy and immunotherapy in addition to their prognosis for bladder cancers.
Publish Date 2023-05-25 16:10
Citation Yang YJ, Xu XQ, Zhang YC, Hu PC, Yang WX. Establishment of a prognostic model related to Tregs and NK cells infiltration in bladder cancer. World J Clin Cases 2023; 11(15): 3444-3456
URL https://www.wjgnet.com/2307-8960/full/v11/i15/3444.htm
DOI https://dx.doi.org/10.12998/wjcc.v11.i15.3444
Full Article (PDF) WJCC-11-3444-with-cover.pdf
Full Article (Word) WJCC-11-3444.docx
Manuscript File 82368_Auto_Edited-LJH-JLW.docx
Answering Reviewers 82368-Answering reviewers.pdf
Audio Core Tip 82368-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 82368-Conflict-of-interest statement.pdf
Copyright License Agreement 82368-Copyright license agreement.pdf
Peer-review Report 82368-Peer-review(s).pdf
Scientific Misconduct Check 82368-Bing-Liu JH-2.png
Scientific Misconduct Check 82368-CrossCheck.png
Scientific Editor Work List 82368-Scientific editor work list.pdf