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4/21/2023 9:16:24 AM | Browse: 196 | Download: 620
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Received |
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2022-12-21 16:12 |
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Peer-Review Started |
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2022-12-21 16:14 |
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To Make the First Decision |
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Return for Revision |
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2023-03-24 05:52 |
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Revised |
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2023-03-24 15:37 |
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Second Decision |
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2023-04-04 03:22 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-04 09:04 |
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Articles in Press |
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2023-04-04 09:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-04-12 00:21 |
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Publish the Manuscript Online |
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2023-04-21 03:41 |
ISSN |
2218-4333 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Hematology |
Manuscript Type |
Minireviews |
Article Title |
Integration of molecular testing for the personalized management of patients with diffuse large B-cell lymphoma and follicular lymphoma
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Manuscript Source |
Invited Manuscript |
All Author List |
Ruth Stuckey, Hugo Luzardo Henríquez, Haridian de la Nuez Melian, José Carlos Rivero Vera, Cristina Bilbao-Sieyro and María Teresa Gómez-Casares |
Funding Agency and Grant Number |
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Corresponding Author |
Cristina Bilbao-Sieyro, PhD, Lecturer, Technician, Department of Hematology, Hospital Universitario de Gran Canaria Dr. Negrin, Barranco de la Ballena, Las Palmas de Gran Canaria 35019, Las Palmas de Gran Canaria, Spain. bilbaocristina@gmail.com |
Key Words |
Next-generation sequencing; Prognosis; Molecular analysis; Targeted therapy; Chimeric antigen receptor T-cell therapy; Personalized medicine |
Core Tip |
Molecular studies in the past decade have improved our understanding of the biological heterogeneity of B-cell lymphomas such as diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma. Next-generation sequencing studies are helping to reveal the different pathogenic pathways affected by each DLBCL subtype and identify new targets for directed therapy. Molecular analysis can also help predict therapeutic outcome to currently available treatments, including chimeric antigen receptor T-cell therapy, and identify candidates for clinical trials with targeted therapies, ultimately leading to improvements in patient outcomes. As such, the incorporation of precision medicine via the integration of molecular analyses in clinical practice can improve clinical outcomes in patients and thus contribute to a new standard of care for patients with B-cell lymphomas. |
Publish Date |
2023-04-21 03:41 |
Citation |
Stuckey R, Luzardo Henríquez H, de la Nuez Melian H, Rivero Vera JC, Bilbao-Sieyro C, Gómez-Casares MT. Integration of molecular testing for the personalized management of patients with diffuse large B-cell lymphoma and follicular lymphoma. World J Clin Oncol 2023; 14(4): 160-170 |
URL |
https://www.wjgnet.com/2218-4333/full/v14/i4/160.htm |
DOI |
https://dx.doi.org/10.5306/wjco.v14.i4.160 |
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