Publication Name	World Journal of Hepatology
Manuscript ID	82791
Country	Czech Republic

Received	2022-12-28 07:33
Peer-Review Started	2022-12-28 07:35
To Make the First Decision
Return for Revision	2023-01-22 19:58
Revised	2023-02-03 21:18
Second Decision	2023-03-22 02:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-03-22 08:12
Articles in Press	2023-03-22 08:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-03-24 06:28
Publish the Manuscript Online	2023-04-20 07:26

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Morphological aspects of small-duct cholangiopathies: A minireview
Manuscript Source	Invited Manuscript
All Author List	Eva Sticova and Ondrej Fabian
Funding Agency and Grant Number
Corresponding Author	Eva Sticova, MD, PhD, Associate Professor, Doctor, Clinical and Transplant Pathology Centre, Institute for Clinical and Experimental Medicine, IKEM, Videnska 1958/9, Prague - 4, Prague 14021, Czech Republic. eva.sticova@ikem.cz
Key Words	Bile duct; Cholangiocytes; Cholangiopathy; Cholangitis; Liver biopsy; Histopathology
Core Tip	A wide range of non-neoplastic and neoplastic conditions affects the small intrahepatic bile ducts. Cholangiopathies account for significant morbidity and mortality and represent an important indication for liver transplantation in adult and paediatric populations. Pathogenesis of most cholangiopathies is complex, and likely involves both environmental and genetic factors. Understanding the underlying pathogenetic mechanisms, knowledge of basic morphological patterns, and an ability to correlate microscopic findings with results obtained by imaging and laboratory methods are important steps in forming an overall clinical picture and selecting the optimal therapeutic approach in patients with biliary diseases. Our minireview addresses some important morphological aspects of small-duct cholangiopathies relevant to the diagnostic process, and also provides a brief overview of the most clinically significant conditions in light of recent progress.
Publish Date	2023-04-20 07:26
Citation	Sticova E, Fabian O. Morphological aspects of small-duct cholangiopathies: A minireview. World J Hepatol 2023; 15(4): 538-553
URL	https://www.wjgnet.com/1948-5182/full/v15/i4/538.htm
DOI	https://dx.doi.org/10.4254/wjh.v15.i4.538

Full Article (PDF)	WJH-15-538.pdf
Full Article (Word)	WJH-15-538.docx
Manuscript File	82791_Auto_Edited-LJH-JLW.docx
Answering Reviewers	82791-Answering reviewers.pdf
Audio Core Tip	82791-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	82791-Conflict-of-interest statement.pdf
Copyright License Agreement	82791-Copyright license agreement.pdf
Peer-review Report	82791-Peer-review(s).pdf
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Scientific Misconduct Check	82791-CrossCheck.png
Scientific Editor Work List	82791-Scientific editor work list.pdf