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6/15/2023 12:47:50 PM | Browse: 108 | Download: 331
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Received |
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2022-12-29 11:13 |
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Peer-Review Started |
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2022-12-29 11:15 |
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To Make the First Decision |
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Return for Revision |
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2023-02-20 01:31 |
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Revised |
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2023-02-21 14:27 |
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Second Decision |
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2023-04-14 03:18 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2023-04-14 09:41 |
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Articles in Press |
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2023-04-14 09:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-22 08:05 |
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Publish the Manuscript Online |
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2023-06-15 12:09 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Impact of interstitial cells of Cajal on slow wave and gallbladder contractility in a guinea pig model of acute cholecystitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fan Ding, Run Guo, Fang Chen, Li-Ping Liu, Zheng-Yu Cui, Yi-Xing Wang, Gang Zhao and Hai Hu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Pudong New Area Clinical Traditional Chinese Medicine of Top Discipline Project |
No. PDZY-2018-0603 |
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| Corresponding Author |
Hai Hu, MD, PhD, Director, Center of Gallbladder Disease, Shanghai East Hospital, School of Medicine, Tongji University, No. 150 Jimo Road, Shanghai 200120, China. huhailc@sina.com |
| Key Words |
Interstitial cells of Cajal; Acute cholecystitis; Slow wave; Gallbladder; Contractility |
| Core Tip |
Acute cholecystitis (AC) is inflammation of the gallbladder. In this study, we found that loss interstitial cells of Cajal (ICCs) could lead to the decreased of gallbladder slow wave (SW) and contractility. Acute inflammation can cause a reduction in the SW and gallbladder motility deficiency by damaging the density and function of ICCs during early AC stage. At the end stage of AC, the decrease of cholecystokinin A receptor and gap junction leads to the further decrease in gallbladder contractility and electrical conductivity. |
| Publish Date |
2023-06-15 12:09 |
| Citation |
Ding F, Guo R, Chen F, Liu LP, Cui ZY, Wang YX, Zhao G, Hu H. Impact of interstitial cells of Cajal on slow wave and gallbladder contractility in a guinea pig model of acute cholecystitis. World J Gastrointest Surg 2023; 15(6): 1068-1079 |
| URL |
https://www.wjgnet.com/1948-9366/full/v15/i6/1068.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v15.i6.1068 |
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