Publication Name	World Journal of Methodology
Manuscript ID	83250
Country	India

Received	2023-01-14 09:58
Peer-Review Started	2023-01-14 09:59
To Make the First Decision
Return for Revision	2023-01-31 08:59
Revised	2023-02-01 05:53
Second Decision	2023-02-10 03:20
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-02-10 09:15
Articles in Press	2023-02-10 09:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-03-14 08:00
Publish the Manuscript Online	2023-03-15 10:35

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Is mandible derived mesenchymal stromal cells superior in proliferation and regeneration to long bone-derived mesenchymal stromal cells?
Manuscript Source	Invited Manuscript
All Author List	Madhan Jeyaraman, Tushar Verma, Naveen Jeyaraman, Bishnu Prasad Patro, Arulkumar Nallakumarasamy and Manish Khanna
Funding Agency and Grant Number
Corresponding Author	Madhan Jeyaraman, MS, PhD, Assistant Professor, Research Associate, Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Chennai 600056, Tamil Nadu, India. madhanjeyaraman@gmail.com
Key Words	Mandible; Long bone; Mesenchymal stromal cells; Osteogenic potential; Regeneration
Core Tip	Due to the difference in the development of long bones and craniofacial bones, the mandibular-derived MSCs (M-MSCs) have distinct differentiation characteristics as compared to that of long bones. In vitro and in vivo animal-based studies demonstrate a higher rate of proliferation and high osteogenic potential for M-MSCs as compared to long-bones MSCs, but in vivo studies in human subjects are lacking. Considering the utility of M-MSCs in the field of orthopaedics, we have discussed various unresolved questions, which need to be explored for their better utility in clinical practice.
Publish Date	2023-03-15 10:35
Citation	Jeyaraman M, Verma T, Jeyaraman N, Patro BP, Nallakumarasamy A, Khanna M. Is mandible derived mesenchymal stromal cells superior in proliferation and regeneration to long bone-derived mesenchymal stromal cells? World J Methodol 2023;13(2): 10-17
URL	https://www.wjgnet.com/2222-0682/full/v13/i2/10.htm
DOI	https://dx.doi.org/10.5662/wjm.v13.i2.10

Full Article (PDF)	WJM-13-10.pdf
Full Article (Word)	WJM-13-10.docx
Manuscript File	83250_Auto_Edited-LJH-JLW.docx
Answering Reviewers	83250-Answering reviewers.pdf
Audio Core Tip	83250-Audio core tip.opus
Conflict-of-Interest Disclosure Form	83250-Conflict-of-interest statement.pdf
Copyright License Agreement	83250-Copyright license agreement.pdf
Peer-review Report	83250-Peer-review(s).pdf
Scientific Misconduct Check	83250-Bing-Liu JH-2.jpg
Scientific Misconduct Check	83250-CrossCheck.jpg
Scientific Editor Work List	83250-Scientific editor work list.pdf
CrossCheck Report	83250-CrossCheck report.pdf