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6/16/2023 6:30:46 AM | Browse: 216 | Download: 805
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Received |
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2023-01-28 06:28 |
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Peer-Review Started |
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2023-01-28 06:32 |
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To Make the First Decision |
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Return for Revision |
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2023-03-28 08:30 |
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Revised |
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2023-04-09 06:34 |
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Second Decision |
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2023-04-18 02:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-18 08:02 |
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Articles in Press |
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2023-04-18 08:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-06-12 01:40 |
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Publish the Manuscript Online |
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2023-06-16 04:00 |
| ISSN |
2308-3840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Public, Environmental & Occupational Health |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Real-world effectiveness of mRNA COVID-19 vaccines in the elderly during the Delta and Omicron variants: Systematic review
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Harvey Palalay, Riddhi Vyas and Barbara Tafuto |
| Funding Agency and Grant Number |
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| Corresponding Author |
Harvey Palalay, MS, RN, Master's Student, Department of Health Informatics, Rutgers University, 675 Hoes Lane West
, Piscataway, NJ 08854, United States. hkp48@shp.rutgers.edu |
| Key Words |
COVID-19; mRNA Vaccine; Effectiveness; Elderly; Delta; Omicron; Systematic review |
| Core Tip |
This systematic review investigates the real-world effectiveness of mRNA coronavirus disease 2019 (COVID-19) vaccines in reducing morbidity and mortality in the elderly during the predominance of Delta and Omicron variants. This study found that the effectiveness of mRNA COVID-19 vaccines in the elderly against the Delta and Omicron variants is marginally lower than what was suggested in clinical trial data. Vaccine efficacy also diminishes over time, indicating the need for a booster dose to restore its effectiveness. Furthermore, to better understand and respond to an epidemic, studies should utilize common outcome measurements or minimize heterogeneity in outcome measures to facilitate data comparison and integration of results. |
| Publish Date |
2023-06-16 04:00 |
| Citation |
Palalay H, Vyas R, Tafuto B. Real-world effectiveness of mRNA COVID-19 vaccines in the elderly during the Delta and Omicron variants: Systematic review. World J Meta-Anal 2023; 11(5): 167-180 |
| URL |
https://www.wjgnet.com/2308-3840/full/v11/i5/167.htm |
| DOI |
https://dx.doi.org/10.13105/wjma.v11.i5.167 |
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