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5/24/2023 10:28:01 AM | Browse: 138 | Download: 345
Publication Name World Journal of Hepatology
Manuscript ID 83540
Country United States
Received
2023-01-29 00:29
Peer-Review Started
2023-01-29 00:33
To Make the First Decision
Return for Revision
2023-02-23 05:20
Revised
2023-03-14 01:09
Second Decision
2023-04-10 03:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-04-10 08:08
Articles in Press
2023-04-10 08:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-05-17 07:46
Publish the Manuscript Online
2023-05-24 09:31
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Noninvasive biomarkers in pediatric nonalcoholic fatty liver disease
Manuscript Source Invited Manuscript
All Author List Dulshan Jayasekera and Phillipp Hartmann
Funding Agency and Grant Number
Funding Agency Grant Number
University of California San Diego Altman Clinical and Translational Research Institute (ACTRI)/NIH grant KL2TR001444
Pinnacle Research Award in Liver Diseases from the American Association for the Study of Liver Diseases Foundation PNC22-159963
National Institutes of Health (NIH) K12 HD85036
the Pilot/Feasibility Grant of the San Diego Digestive Diseases Research Center (SDDRC) P30 DK120515 (to P.H.)
Corresponding Author Phillipp Hartmann, MD, Assistant Professor, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, United States. phhartmann@health.ucsd.edu
Key Words Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Steatosis; Fibrosis; Serological; Imaging
Core Tip Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in children and adolescents worldwide. Early diagnosis is essential and currently, liver biopsy is the gold standard for diagnosis and staging. However, noninvasive serological biomarkers, composite scores, and imaging biomarkers are being extensively studied for the diagnosis of NAFLD, nonalcoholic steatohepatitis (NASH), and liver fibrosis in children. This work reviews recent research on noninvasive biomarkers in pediatric NAFLD, identifies circulating biomarkers and imaging techniques that show the most promise, and suggests topics for future research.
Publish Date 2023-05-24 09:31
Citation Jayasekera D, Hartmann P. Noninvasive biomarkers in pediatric nonalcoholic fatty liver disease. World J Hepatol 2023; 15(5): 609-640
URL https://www.wjgnet.com/1948-5182/full/v15/i5/609.htm
DOI https://dx.doi.org/10.4254/wjh.v15.i5.609
Full Article (PDF) WJH-15-609.pdf
Full Article (Word) WJH-15-609.docx
Manuscript File 83540_Auto_Edited-LJH-JLW.docx
Answering Reviewers 83540-Answering reviewers.pdf
Audio Core Tip 83540-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 83540-Conflict-of-interest statement.pdf
Copyright License Agreement 83540-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 83540-Grant application form(s).pdf
Peer-review Report 83540-Peer-review(s).pdf
Scientific Misconduct Check 83540-Bing-Liu JH-2.png
Scientific Misconduct Check 83540-CrossCheck.png
Scientific Editor Work List 83540-Scientific editor work list.pdf
CrossCheck Report 83540-CrossCheck report.pdf