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5/16/2023 1:01:02 PM | Browse: 183 | Download: 683
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Received |
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2023-02-17 12:45 |
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Peer-Review Started |
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2023-02-17 12:47 |
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To Make the First Decision |
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Return for Revision |
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2023-03-24 18:28 |
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Revised |
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2023-03-28 13:46 |
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Second Decision |
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2023-04-24 02:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-24 08:53 |
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Articles in Press |
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2023-04-24 08:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-09 23:58 |
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Publish the Manuscript Online |
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2023-05-16 07:16 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Association of vitamin D and polymorphisms of its receptor with antiviral therapy in pregnant women with hepatitis B
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rui Wang, Xia Zhu, Xuan Zhang, Huan Liu, Yu-Lin Ji and Yong-Hua Chen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Key Research and Development Projects in Sichuan Province |
2021YFS0168 |
| The National Scientific and Technological Major Project for Infectious Diseases Control in China |
2018ZX10715-003 |
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| Corresponding Author |
Yong-Hua Chen, MD, PhD, Associate Professor, Division of Pancreatic Surgery, Department of General Surgery, West China Hospital of Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu CN 610041, Sichuan Province, China. chenyonghua2007@163.com |
| Key Words |
Hepatitis B virus; Vitamin D; Vitamin D receptor polymorphism; Antiviral therapy; Pregnancy; Mother-to-child transmission |
| Core Tip |
This retrospective study investigated the influence of vitamin D (VD) levels and single nucleotide polymorphisms of the VD receptor gene (VDR SNPs) on the efficacy of tenofovir disoproxil fumarate in preventing mother-to-child transmission in 38 pregnant women with high hepatitis B viral loads. We demonstrate a significant association between low serum levels of 25-hydroxyvitamin D and high levels of hepatitis B virus replication in pregnant women with high hepatitis B viral loads, and maternal VD levels as well as VDR SNPs may be associated with the efficacy of antiviral therapy. |
| Publish Date |
2023-05-16 07:16 |
| Citation |
Wang R, Zhu X, Zhang X, Liu H, Ji YL, Chen YH. Association of vitamin D and polymorphisms of its receptor with antiviral therapy in pregnant women with hepatitis B. World J Gastroenterol 2023; 29(19): 3003-3012 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i19/3003.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i19.3003 |
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