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7/27/2023 2:44:42 AM | Browse: 179 | Download: 361
Publication Name World Journal of Clinical Cases
Manuscript ID 84231
Country China
Received
2023-03-03 13:43
Peer-Review Started
2023-03-03 13:46
To Make the First Decision
Return for Revision
2023-05-19 02:14
Revised
2023-06-01 03:42
Second Decision
2023-06-26 02:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-06-26 07:00
Articles in Press
2023-06-26 07:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
2023-07-02 14:14
Typeset the Manuscript
2023-07-17 00:25
Publish the Manuscript Online
2023-07-27 01:26
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Identification of function genes regulating gastric cancer progression using integrated bioinformatics analysis
Manuscript Source Unsolicited Manuscript
All Author List Kun Yu, Dong Zhang, Qiang Yao, Xing Pan, Gang Wang, Hai-Yang Qian, Yao Xiao, Qiong Chen and Ke Mei
Funding Agency and Grant Number
Corresponding Author Qiong Chen, MD, Doctor, Department of Radiology, Shanghai Xuhui Dahua Hospital, No. 901 Lao'humin Road, Xuhui District, Shanghai 200090, China. cq1444@sina.com
Key Words Gastric cancer; Bioinformatics analysis; Differentially expressed gene; Protein-protein interaction network; Cisplatin resistance
Core Tip Gastric cancer (GC) is one of the most common malignancies of the digestive system with few genetic markers for its early detection and prevention. 348 GC tissues and 141 normal tissues were analysed; 251 differently expressed genes were focused, which contained 187 down-regulated genes and 64 up-regulated genes. Recognition of significantly upregulated genes with poor prognosis in GC using integrated bioinformatics methods were detected. Further, molecular mechanism of GC via Bioinformatics Analysis showed three DEGs (BIRC5, TRIP13, or UBE2C) which play key roles in the progression of CG.
Publish Date 2023-07-27 01:26
Citation Yu K, Zhang D, Yao Q, Pan X, Wang G, Qian HY, Xiao Y, Chen Q, Mei K. Identification of functional genes regulating gastric cancer progression using integrated bioinformatics analysis. World J Clin Cases 2023; 11(21): 5023-5034
URL https://www.wjgnet.com/2307-8960/full/v11/i21/5023.htm
DOI https://dx.doi.org/10.12998/wjcc.v11.i21.5023
Full Article (PDF) WJCC-11-5023-with-cover.pdf
Full Article (Word) WJCC-11-5023.docx
Manuscript File 84231_Auto_Edited-JLW-Language editing-Webster J-Clear.docx
Answering Reviewers 84231-Answering reviewers.pdf
Audio Core Tip 84231-Audio core tip.mp3
Biostatistics Review Certificate 84231-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 84231-Conflict-of-interest statement.pdf
Copyright License Agreement 84231-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 84231-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 84231-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 84231-Language certificate.pdf
Supplementary Material 84231-Supplementary material.pdf
Peer-review Report 84231-Peer-review(s).pdf
Scientific Misconduct Check 84231-Bing-Chen YL-2.png
Scientific Editor Work List 84231-Scientific editor work list.pdf