Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	84996
Country	China

Received	2023-04-07 08:25
Peer-Review Started	2023-04-07 08:28
To Make the First Decision
Return for Revision	2023-07-19 17:43
Revised	2023-07-31 01:24
Second Decision	2023-08-18 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-08-18 09:13
Articles in Press	2023-08-18 09:13
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-08-17 01:16
Typeset the Manuscript	2023-08-31 09:53
Publish the Manuscript Online	2023-09-13 09:17

ISSN	1948-5204 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Xue-Jun Wang, Yong Liu, Bin Ke, Li Zhang and Han Liang
Funding Agency and Grant Number	Funding Agency Grant Number National Key R&D Program of China No. 2016YFC1303200
Corresponding Author	Xue-Jun Wang, MD, Professor, Department of Gastric Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin Key Laboratory of Digestive Cancer, Huanhu Xi Road, Tiyuan Bei, Hexi District, Tianjin 300060, China. wangxuejun20202020@163.com
Key Words	Integrin binding sialoprotein; Cleavage and polyadenylation factor 6; Pyroptosis; Gastric cancer
Core Tip	This study, for the first time, revealed the crucial role of the cleavage and polyadenylation factor 6 (CPSF6)/integrin binding sialoprotein (IBSP) axis in gastric cancer (GC). This discovery might shed light on GC treatment. However, although this study explored this regulatory axis on cell proliferation, metastasis, and pyroptosis in GC, its data regarding the regulatory effects of CPSF6/IBSP on GC progression are limited. In the future, the regulatory effects of the CPSF6/IBSP axis on stemness, autophagy, and inflammation should be investigated through more experiments.
Publish Date	2023-09-13 09:17
Citation	Wang XJ, Liu Y, Ke B, Zhang L, Liang H. RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer. World J Gastrointest Oncol 2023; 15(9): 1531-1543
URL	https://www.wjgnet.com/1948-5204/full/v15/i9/1531.htm
DOI	https://dx.doi.org/10.4251/wjgo.v15.i9.1531

Full Article (PDF)	WJGO-15-1531-with-cover.pdf
Full Article (Word)	WJGO-15-1531.docx
Manuscript File	84996_Auto_Edited-YLC-Wang TQ-JLW.docx
Answering Reviewers	84996-Answering reviewers.pdf
Audio Core Tip	84996-Audio core tip.mp3
Biostatistics Review Certificate	84996-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	84996-Conflict-of-interest statement.pdf
Copyright License Agreement	84996-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	84996-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	84996-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	84996-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	84996-Language certificate.pdf
Supplementary Material	84996-Supplementary material.pdf
Peer-review Report	84996-Peer-review(s).pdf
Scientific Misconduct Check	84996-Bing-Chen YL-2.png
Scientific Editor Work List	84996-Scientific editor work list.pdf
CrossCheck Report	84996-CrossCheck report.pdf