Publication Name	World Journal of Clinical Cases
Manuscript ID	85070
Country	China

Received	2023-04-10 13:42
Peer-Review Started	2023-04-10 13:44
To Make the First Decision
Return for Revision	2023-05-12 01:23
Revised	2023-05-22 04:44
Second Decision	2023-05-31 03:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-05-31 07:52
Articles in Press	2023-05-31 07:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-06-19 04:03
Publish the Manuscript Online	2023-06-30 12:54

ISSN	2307-8960 (online)
Open Access
Copyright
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Category	Hematology
Manuscript Type	Case Report
Article Title	Tuberculosis-induced aplastic crisis and atypical lymphocyte expansion in advanced myelodysplastic syndrome: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Yun Sun, Xiao-Dong Yang, Jia Xu, Nuan-Nuan Xiu, Bo Ju and Xi-Chen Zhao
Funding Agency and Grant Number	Funding Agency Grant Number The Specialized Scientific Research Fund Projects of The Medical Group of Qingdao University No: YLJT20201002
Corresponding Author	Xi-Chen Zhao, MD, Chief Physician, Department of Hematology, The Central Hospital of Qingdao West Coast New Area, No 9, Huangpujiang Road, Qingdao 266555, Shandong Province, China. zhaoxichen2003@163.com
Key Words	Case report; Myelodysplastic syndrome; Aplastc crisis; Atypical lymphocyte; Leukemic cell regression; CD56+ lymphocyte expansion; Disseminated tuberculosis
Core Tip	In patients with myelodysplastic syndrome, bone marrow cellularity and myeloblasts usually increase with disease progression. An advanced myelodysplastic syndrome patient experienced an episode of aplastic crisis. During the aplastic crisis, leukemic cells regressed. The bone marrow was infiltrated with atypical lymphocytes that expressed high frequencies of cluster of differentiation (CD)3, CD5, CD8, CD16, CD56 and CD57. Antituberculosis treatment led to reversion of the aplastic crisis, disappearance of the atypical lymphocytes, increased marrow cellularity and 2 mo of hematological remission, suggesting that disseminated tuberculosis was responsible for the development of aplastic crisis, regression of leukemic cells and activation of CD56+ cells.
Publish Date	2023-06-30 12:54
Citation	Sun XY, Yang XD, Xu J, Xiu NN, Ju B, Zhao XC. Tuberculosis-induced aplastic crisis and atypical lymphocyte expansion in advanced myelodysplastic syndrome: A case report and review of literature. World J Clin Cases 2023; 11(19): 4713-4722
URL	https://www.wjgnet.com/2307-8960/full/v11/i19/4713.htm
DOI	https://dx.doi.org/10.12998/wjcc.v11.i19.4713

Full Article (PDF)	WJCC-11-4713-with-cover.pdf
Full Article (Word)	WJCC-11-4713.docx
Manuscript File	85070_Auto_Edited-JLW.docx
Answering Reviewers	85070-Answering reviewers.pdf
Audio Core Tip	85070-Audio core tip.wav
Conflict-of-Interest Disclosure Form	85070-Conflict-of-interest statement.pdf
Copyright License Agreement	85070-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	85070-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s)	85070-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	85070-Language certificate.pdf
Peer-review Report	85070-Peer-review(s).pdf
Scientific Misconduct Check	85070-Bing-Ma YJ-2.jpg
Scientific Editor Work List	85070-Scientific editor work list.pdf