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9/15/2023 10:22:42 AM | Browse: 594 | Download: 1520
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Received |
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2023-05-19 09:32 |
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Peer-Review Started |
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2023-05-19 09:32 |
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First Decision by Editorial Office Director |
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2023-06-01 08:46 |
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Return for Revision |
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2023-06-01 08:46 |
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Revised |
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2023-07-04 06:22 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-07-28 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-07-28 07:20 |
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Articles in Press |
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2023-07-28 07:20 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-09-08 07:43 |
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Publish the Manuscript Online |
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2023-09-15 10:15 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Basic Study |
| Article Title |
Hippocampus protection from apoptosis by Baicalin in a LiCl-pilocarpine-induced rat status epilepticus model through autophagy activation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bin Yang, Han-Yu Wen, Ri-Sheng Liang, Ting-Ming Lu, Zheng-Yan Zhu and Chun-Hua Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Fujian Province of China |
2019J01317 |
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| Corresponding Author |
Ri-Sheng Liang, PhD, Professor, Department of Neurosurgery, Affiliated Union Hospital of Fujian Medical University, Neurosurgery Research Institute of Fujian Province, No. 29 Xinquan Road, Fuzhou 350001, Fujian Province, China. doctorlr@126.com |
| Key Words |
Baicalin; Status epilepticus; Autophagy; Mitochondrial apoptosis |
| Core Tip |
This study established the rat model of status epilepticus by intraperitoneally injecting LiCl-pilocarpine. Then, Baicalin was administered to the rats for treatment. The pathological changes of hippocampal were observed. Western blotting and terminal deoxynucleotidyl transferase dUTP nick end labeling assays were used to verify the inhibitory effect of Baicalin on apoptosis of rat hippocampal neuronal cells. We have drawn the conclusion that Baicalin protects the hippocampus from apoptosis. |
| Publish Date |
2023-09-15 10:15 |
| Citation |
Yang B, Wen HY, Liang RS, Lu TM, Zhu ZY, Wang CH. Hippocampus protection from apoptosis by Baicalin in a LiCl-pilocarpine-induced rat status epilepticus model through autophagy activation. World J Psychiatry 2023; 13(9): 620-629
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| URL |
https://www.wjgnet.com/2220-3206/full/v13/i9/620.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v13.i9.620 |
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