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9/15/2023 10:22:42 AM | Browse: 195 | Download: 340
Publication Name World Journal of Psychiatry
Manuscript ID 85267
Country China
Received
2023-05-19 09:32
Peer-Review Started
2023-05-19 09:32
To Make the First Decision
Return for Revision
2023-06-01 08:46
Revised
2023-07-04 06:22
Second Decision
2023-07-28 02:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-07-28 07:20
Articles in Press
2023-07-28 07:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-09-08 07:43
Publish the Manuscript Online
2023-09-15 10:15
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neurosciences
Manuscript Type Basic Study
Article Title Hippocampus protection from apoptosis by Baicalin in a LiCl-pilocarpine-induced rat status epilepticus model through autophagy activation
Manuscript Source Unsolicited Manuscript
All Author List Bin Yang, Han-Yu Wen, Ri-Sheng Liang, Ting-Ming Lu, Zheng-Yan Zhu and Chun-Hua Wang
Funding Agency and Grant Number
Funding Agency Grant Number
Natural Science Foundation of Fujian Province of China 2019J01317
Corresponding Author Ri-Sheng Liang, PhD, Professor, Department of Neurosurgery, Affiliated Union Hospital of Fujian Medical University, Neurosurgery Research Institute of Fujian Province, No. 29 Xinquan Road, Fuzhou 350001, Fujian Province, China. doctorlr@126.com
Key Words Baicalin; Status epilepticus; Autophagy; Mitochondrial apoptosis
Core Tip This study established the rat model of status epilepticus by intraperitoneally injecting LiCl-pilocarpine. Then, Baicalin was administered to the rats for treatment. The pathological changes of hippocampal were observed. Western blotting and terminal deoxynucleotidyl transferase dUTP nick end labeling assays were used to verify the inhibitory effect of Baicalin on apoptosis of rat hippocampal neuronal cells. We have drawn the conclusion that Baicalin protects the hippocampus from apoptosis.
Publish Date 2023-09-15 10:15
Citation Yang B, Wen HY, Liang RS, Lu TM, Zhu ZY, Wang CH. Hippocampus protection from apoptosis by Baicalin in a LiCl-pilocarpine-induced rat status epilepticus model through autophagy activation. World J Psychiatry 2023; 13(9): 620-629
URL https://www.wjgnet.com/2220-3206/full/v13/i9/620.htm
DOI https://dx.doi.org/10.5498/wjp.v13.i9.620
Full Article (PDF) WJP-13-620-with-cover.pdf
Full Article (Word) WJP-13-620.docx
The ARRIVE Guidelines 85267-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 85267_Auto_Edited-JLW.docx
Answering Reviewers 85267-Answering reviewers.pdf
Audio Core Tip 85267-Audio core tip.mp3
Biostatistics Review Certificate 85267-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 85267-Conflict-of-interest statement.pdf
Copyright License Agreement 85267-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 85267-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 85267-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate 85267-Language certificate.pdf
Peer-review Report 85267-Peer-review(s).pdf
Scientific Misconduct Check 85267-Bing-Fan JR-2.png
Scientific Editor Work List 85267-Scientific editor work list.pdf
CrossCheck Report 85267-CrossCheck report.pdf
CrossCheck Report 85267-CrossCheck.png