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10/10/2023 9:20:03 AM | Browse: 361 | Download: 1187
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Received |
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2023-05-21 02:24 |
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Peer-Review Started |
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2023-05-21 02:24 |
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First Decision by Editorial Office Director |
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2023-06-01 08:42 |
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Return for Revision |
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2023-06-01 08:42 |
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Revised |
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2023-07-05 09:15 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-08-31 07:12 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-08-31 07:33 |
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Articles in Press |
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2023-08-31 07:33 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-09-27 10:48 |
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Publish the Manuscript Online |
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2023-10-10 08:15 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Pomolic acid and its glucopyranose ester promote apoptosis through autophagy in HT-29 colon cancer cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Yan Liu, Teng-Hua Yu, Tie-Song Liao, Peng Xu, Ying Wang, Min Shi and Bin Li |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Central Level Major Increase and Decrease Expenditures Project |
No. 2060302-2101-11, No. 2060302-1701-01 |
| Workstation Project |
No. YSGZZ201801 |
| Open Fund for Scientific Research of Jiangxi Cancer Hospital |
No. 2021J16 |
| Distinguished Young Scholars Fund of Jiangxi Cancer Hospital |
No. 2021DYS04 |
| Jiangxi Provincial Natural Science Foundation |
No. 20212BAB216063 |
| National Natural Science Foundation of China |
No. 82160565 |
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| Corresponding Author |
Bin Li, PhD, Professor, Workstation of Academician, Jiangxi University of Chinese Medicine, No. 1688 Meiling Road, Nanchang 330004, Jiangxi Province, China. emilylly2013@sina.com |
| Key Words |
Colon cancer; Achyrocline satureioides; Pomolic acid; Pomolic acid-28-O-β-D-glucopyranose |
| Core Tip |
Compounds pomolic acid (PA) and pomolic acid-28-O-β-D-glucopyranosyl ester (PAO) exhibited a considerable growth inhibitory effect against HT-29 cell lines in a time-dose-dependent manner. PA and PAO promote apoptosis through autophagy in HT-29 colon tumor cells. Both PA and PAO provide novel therapeutic strategy for colorectal cancers treatment. |
| Publish Date |
2023-10-10 08:15 |
| Citation |
Liu LY, Yu TH, Liao TS, Xu P, Wang Y, Shi M, Li B. Pomolic acid and its glucopyranose ester promote apoptosis through autophagy in HT-29 colon cancer cells. World J Gastrointest Oncol 2023; 15(10): 1756-1770
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| URL |
https://www.wjgnet.com/1948-5204/full/v15/i10/1756.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v15.i10.1756 |
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