Publication Name	World Journal of Gastroenterology
Manuscript ID	85421
Country	Brazil

Received	2023-04-28 20:14
Peer-Review Started	2023-04-28 20:16
To Make the First Decision
Return for Revision	2023-06-17 03:51
Revised	2023-07-01 19:38
Second Decision	2023-07-21 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-07-24 00:55
Articles in Press	2023-07-24 00:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-08-02 03:41
Publish the Manuscript Online	2023-08-10 13:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Immunology
Manuscript Type	Review
Article Title	Immune response modulation in inflammatory bowel diseases by Helicobacter pylori infection
Manuscript Source	Invited Manuscript
All Author List	Gabriella Feilstrecker Balani, Mariana dos Santos Cortez, Jayme Euclydes Picasky da Silveira Freitas, Fabrício Freire de Melo, Ana Carla Zarpelon-Schutz and Kádima Nayara Teixeira
Funding Agency and Grant Number
Corresponding Author	Kádima Nayara Teixeira, PhD, Professor, Campus Toledo, Universidade Federal do Paraná, Max Planck 3796, Toledo 85.919-899, Paraná, Brazil. kadimateixeira@ufpr.br
Key Words	Cytotoxin-associated antigen A oncoprotein; Gut microbiota; Helicobacter pylori; Helicobacter pylori neutrophil-activating protein; Immunological modulation; Inflammatory bowel disease; NLR family pyrin domain containing 3 inflammasome
Core Tip	Helicobacter pylori (H. pylori) infection seems to modulate the immune response triggered by inflammatory bowel disease in a way that makes it less aggressive. The virulence factors of H. pylori, as well as the mechanisms that allow it to remain in the stomach environment, appear to change the intestinal microenvironment and modulate the local immune response, contributing to a disease with milder symptoms and less tissue damage.
Publish Date	2023-08-10 13:26
Citation	Feilstrecker Balani G, dos Santos Cortez M, Picasky da Silveira Freitas JE, Freire de Melo F, Zarpelon-Schutz AC, Teixeira KN. Immune response modulation in inflammatory bowel diseases by Helicobacter pylori infection. World J Gastroenterol 2023; 29(30): 4604-4615
URL	https://www.wjgnet.com/1007-9327/full/v29/i30/4604.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i30.4604

Full Article (PDF)	WJG-29-4604-with-cover.pdf
Full Article (Word)	WJG-29-4604.docx
Manuscript File	85421_Auto_Edited-JLW.docx
Answering Reviewers	85421-Answering reviewers.pdf
Audio Core Tip	85421-Audio core tip.aac
Conflict-of-Interest Disclosure Form	85421-Conflict-of-interest statement.pdf
Copyright License Agreement	85421-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	85421-Language certificate.pdf
Peer-review Report	85421-Peer-review(s).pdf
Scientific Misconduct Check	85421-Bing-Wang JJ-2.png
Scientific Editor Work List	85421-Scientific editor work list.pdf
CrossCheck Report	85421-CrossCheck report.pdf