Publication Name	World Journal of Gastroenterology
Manuscript ID	85686
Country	Thailand

Received	2023-05-10 07:42
Peer-Review Started	2023-05-10 07:44
To Make the First Decision
Return for Revision	2023-07-09 03:05
Revised	2023-07-18 07:17
Second Decision	2023-07-28 02:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-07-28 07:41
Articles in Press	2023-07-28 07:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-08-03 06:19
Publish the Manuscript Online	2023-08-10 13:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Systemic treatments for resectable carcinoma of the esophagus
Manuscript Source	Invited Manuscript
All Author List	Wattana Leowattana, Pathomthep Leowattana and Tawithep Leowattana
Funding Agency and Grant Number
Corresponding Author	Wattana Leowattana, BMed, MD, MSc, PhD, Professor, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajavithi road, Rachatawee 10400, Bangkok, Thailand. wattana.leo@mahidol.ac.th
Key Words	Systemic treatment; Resectable carcinoma of the esophagus; Personalized medicine; Biomarkers; Chemotherapy; Chemoradiotherapy; Immunotherapy; Immune checkpoint inhibitors
Core Tip	Despite improvements in neoadjuvant and adjuvant treatment approaches in recent years, the average life expectancy of patients with resectable esophageal cancer (EC) still falls below 5 years. Immunotherapy has been effectively used as a first-line therapy for many oncological diseases at advanced stages for over ten years. Immunotherapy drugs are also making great progress in resectable situations, while it is still debatable whether this treatment should be limited to a certain patient subgroup based on biomarker selection. In order to treat resectable EC, immunotherapy, in particular immune checkpoint inhibitors, has made significant strides. This review also provides a brief overview of potential ongoing clinical studies.
Publish Date	2023-08-10 13:26
Citation	Leowattana W, Leowattana P, Leowattana T. Systemic treatments for resectable carcinoma of the esophagus. World J Gastroenterol 2023; 29(30): 4628-4641
URL	https://www.wjgnet.com/1007-9327/full/v29/i30/4628.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i30.4628

Full Article (PDF)	WJG-29-4628-with-cover.pdf
Full Article (Word)	WJG-29-4628.docx
Manuscript File	85686_Auto_Edited-JLW.docx
Answering Reviewers	85686-Answering reviewers.pdf
Audio Core Tip	85686-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	85686-Conflict-of-interest statement.pdf
Copyright License Agreement	85686-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	85686-Language certificate.pdf
Peer-review Report	85686-Peer-review(s).pdf
Scientific Misconduct Check	85686-Bing-Lin C-2.png
Scientific Editor Work List	85686-Scientific editor work list.pdf