Publication Name	World Journal of Clinical Oncology
Manuscript ID	85789
Country	United Kingdom

Received	2023-05-16 06:38
Peer-Review Started	2023-05-16 06:41
To Make the First Decision
Return for Revision	2023-05-25 03:51
Revised	2023-06-07 03:20
Second Decision	2023-06-21 02:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-06-21 09:03
Articles in Press	2023-06-21 09:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-07-17 01:41
Publish the Manuscript Online	2023-07-19 06:45

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Stromal inflammation, fibrosis and cancer: An old intuition with promising potential
Manuscript Source	Invited Manuscript
All Author List	Oliver Oey, Angela Felicia Sunjaya, Yasir Khan and Andrew Redfern
Funding Agency and Grant Number
Corresponding Author	Angela Felicia Sunjaya, BMed, MD, Master's Student, Researcher, Institute of Cardiovascular Science, University College London, 62 Huntley St, London WC1E 6DD, United Kingdom. angelafelicia.s@gmail.com
Key Words	Inflammation; Fibrosis; Tumour microenvironment; Stroma; Cancer
Core Tip	Chronic inflammation and fibrosis have long been postulated to be involved in carcinogenesis via numerous mechanisms including but not limited to growth factor/cytokine-mediated cellular proliferation, apoptotic resistance, immunosuppression; and free-radical-induced oxidative deoxyribonucleic acid damage. In this review, we discuss various inflammatory and/or fibrotic conditions that have been associated with increased cancer risk, with particular emphasis on their pathophysiology. We also review various therapeutic agents and specific cancer screening that could be applicable in reducing the incidence of cancers developing from the corresponding inflammatory and/or fibrotic conditions, thereby reducing morbidity and mortality.
Publish Date	2023-07-19 06:45
Citation	Oey O, Sunjaya AF, Khan Y, Redfern A. Stromal inflammation, fibrosis and cancer: An old intuition with promising potential. World J Clin Oncol 2023; 14(7): 230-246
URL	https://www.wjgnet.com/2218-4333/full/v14/i7/230.htm
DOI	https://dx.doi.org/10.5306/wjco.v14.i7.230

Full Article (PDF)	WJCO-14-230-with-cover.pdf
Full Article (Word)	WJCO-14-230.docx
Manuscript File	85789_Auto_Edited-LJH-JLW.docx
Answering Reviewers	85789-Answering reviewers.pdf
Audio Core Tip	85789-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	85789-Conflict-of-interest statement.pdf
Copyright License Agreement	85789-Copyright license agreement.pdf
Peer-review Report	85789-Peer-review(s).pdf
Scientific Misconduct Check	85789-Bing-Liu JH-2.png
Scientific Misconduct Check	85789-CrossCheck.png
Scientific Editor Work List	85789-Scientific editor work list.pdf