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10/19/2023 4:29:57 PM | Browse: 225 | Download: 743
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Received |
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2023-05-26 15:31 |
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Peer-Review Started |
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2023-05-26 15:33 |
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To Make the First Decision |
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Return for Revision |
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2023-07-23 22:35 |
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Revised |
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2023-08-13 03:10 |
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Second Decision |
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2023-10-09 00:54 |
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Accepted by Journal Editor-in-Chief |
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2023-10-11 20:54 |
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Accepted by Executive Editor-in-Chief |
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2023-10-16 08:12 |
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Articles in Press |
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2023-10-16 08:12 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-09-30 23:52 |
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Typeset the Manuscript |
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2023-10-18 00:38 |
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Publish the Manuscript Online |
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2023-10-19 16:26 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Function and biomedical implications of exosomal microRNAs delivered by parenchymal and nonparenchymal cells in hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hai-Chen Wang, Wen-Xuan Yin, Meng Jiang, Jia-Yi Han, Xing-Wang Kuai, Rui Sun, Yu-Feng Sun and Ju-Ling Ji |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81761128018 |
| National Natural Science Foundation of China |
81572871 |
| Natural Science Foundation of Jiangsu Province |
BK20151277 |
| Undergraduate Training Programs for Innovation and Entrepreneurship of Jiangsu Province |
202110304035Z |
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| Corresponding Author |
Ju-Ling Ji, MD, PhD, Professor, Department of Pathology, Medical School of Nantong University, No. 19 Qixiu Road, Nantong 226001, Jiangsu Province, China. jijuling@ntu.edu.cn |
| Key Words |
Hepatocellular carcinoma; MicroRNA; Exosomes; Extracellular vesicles; Nonparenchymal cells |
| Core Tip |
Hepatocellular carcinoma (HCC) is one of the most serious cancers in adults, and microRNAs (miRNAs) in small extracellular vesicles (exosomes) play a vital role in the pathological processes of HCC. Recent studies on exosomal miRNAs in HCC mainly focus on miRNA profiling but place little emphasis on where miRNAs come from and what target cells they act on. This review focused on the origin of exosomal miRNAs according to their parent cells in the tumor microenvironment and their role in HCC pathogenesis, contributing to a better understanding of exosomal miRNAs in the tumor microenvironment. |
| Publish Date |
2023-10-19 16:26 |
| Citation |
Wang HC, Yin WX, Jiang M, Han JY, Kuai XW, Sun R, Sun YF, Ji JL. Function and biomedical implications of exosomal microRNAs delivered by parenchymal and nonparenchymal cells in hepatocellular carcinoma. World J Gastroenterol 2023; 29(39): 5435-5451 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i39/5435.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i39.5435 |
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