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10/26/2023 6:41:55 AM | Browse: 226 | Download: 436
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Received |
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2023-07-27 03:30 |
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Peer-Review Started |
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2023-07-27 03:30 |
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To Make the First Decision |
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Return for Revision |
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2023-08-15 18:03 |
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Revised |
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2023-09-23 09:58 |
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Second Decision |
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2023-10-10 02:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2023-10-17 08:11 |
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Articles in Press |
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2023-10-17 08:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-10-24 09:41 |
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Publish the Manuscript Online |
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2023-10-26 02:16 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Basic Study |
| Article Title |
MicroRNA-584-5p/RUNX family transcription factor 2 axis mediates hypoxia-induced osteogenic differentiation of periosteal stem cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Jia Lu, Xiao-Jian Shi, Qiang Fu, Yong-Chuan Li, Lei Zhu and Nan Lu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Sailing Program of Naval Medical University, Program of Shanghai Hongkou District Health Commission |
2202-27 |
| Special Funds for Activating Scientific Research of Shanghai Fourth People’s Hospital |
sykyqd05801 |
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| Corresponding Author |
Nan Lu, PhD, Doctor, Department of Orthopedic Trauma Surgery, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, No. 1279 Sanmen Road, Hongkou District, Shanghai 200001, China. nanlu_1981@163.com |
| Key Words |
Periosteal stem cell; Osteogenic differentiation; RUNX family transcription factor 2; MiroRNA-584-5p |
| Core Tip |
This study simulated the hypoxic environment of periosteal stem cells (PSCs) during fracture and examined the related cellular responses to the hypoxia-induced PSC osteogenic differentiation. Importantly, the microRNA-584-5p/RUNX family transcription factor 2 axis was determined to be one of the regulating mechanisms for the hypoxia-induced PSC osteogenic differentiations. |
| Publish Date |
2023-10-26 02:16 |
| Citation |
Lu JJ, Shi XJ, Fu Q, Li YC, Zhu L, Lu N. MicroRNA-584-5p/RUNX family transcription factor 2 axis mediates hypoxia-induced osteogenic differentiation of periosteal stem cells. World J Stem Cells 2023; 15(10): 979-988 |
| URL |
https://www.wjgnet.com/1948-0210/full/v15/i10/979.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v15.i10.979 |
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