Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	86473
Country	China

Received	2023-10-11 10:43
Peer-Review Started	2023-10-11 10:45
To Make the First Decision
Return for Revision	2023-12-11 01:40
Revised	2023-12-24 15:51
Second Decision	2024-01-18 02:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-01-18 05:35
Articles in Press	2024-01-18 05:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-02-06 01:32
Publish the Manuscript Online	2024-02-25 15:12

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Systematic Reviews
Article Title	Comparative effectiveness of several adjuvant therapies after hepatectomy for hepatocellular carcinoma patients with microvascular invasion
Manuscript Source	Unsolicited Manuscript
All Author List	Yin-Xuan Pei, Chen-Guang Su, Zheng Liao, Wei-Wei Li, Zi-Xiang Wang and Jin-Long Liu
Funding Agency and Grant Number
Corresponding Author	Jin-Long Liu, MD, Chief Doctor, Department of Hepatobiliary Surgery, The Affiliated Hospital of Chengde Medical University, No. 36 Nanyingzi Street, Shuangqiao District, Chengde 067000, Hebei Province, China. liujl800813@163.com
Key Words	Hepatocellular carcinoma; Adjuvant therapy; Network meta-analysis; Transarterial chemoembolization; Hepatic artery infusion chemotherapy; Radiotherapy; Sorafenib
Core Tip	This study represents the inaugural network meta-analysis examining the efficacy of postoperative adjuvant therapies in individuals with hepatocellular carcinoma featuring microvascular invasion who underwent curative hepatectomy. Comparing four distinct postoperative adjuvant strategies-transarterial chemoembolization, sorafenib, hepatic artery infusion chemotherapy, and radiotherapy (RT)-we assessed their impact on recurrence free survival and overall survival (OS). The outcomes unveiled that RT emerges as the most effective adjuvant therapy, significantly reducing recurrence risk and extending OS.
Publish Date	2024-02-25 15:12
Citation	Pei YX, Su CG, Liao Z, Li WW, Wang ZX, Liu JL. Comparative effectiveness of several adjuvant therapies after hepatectomy for hepatocellular carcinoma patients with microvascular invasion. World J Gastrointest Surg 2024; 16(2): 554-570
URL	https://www.wjgnet.com/1948-9366/full/v16/i2/554.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i2.554

Full Article (PDF)	WJGS-16-554-with-cover.pdf
Full Article (Word)	WJGS-16-554.docx
PRISMA 2009 Checklist	86473-PRISMA 2009 Checklist.pdf
Manuscript File	86473_Auto_Edited-YJP.docx
Answering Reviewers	86473-Answering reviewers.pdf
Audio Core Tip	86473-Audio core tip.mp3
Biostatistics Review Certificate	86473-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	86473-Conflict-of-interest statement.pdf
Copyright License Agreement	86473-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	86473-Language certificate.pdf
Peer-review Report	86473-Peer-review(s).pdf
Scientific Misconduct Check	86473-Bing-Wang JJ-2.png
Scientific Editor Work List	86473-Scientific editor work list.pdf
CrossCheck Report	86473-CrossCheck report.pdf