Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	86515
Country	China

Received	2023-06-23 06:31
Peer-Review Started	2023-06-23 06:34
First Decision by Editorial Office Director	2023-08-30 16:29
Return for Revision	2023-08-30 16:29
Revised	2023-09-12 13:46
Publication Fee Transferred
Second Decision by Editor	2023-10-11 01:11
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2023-10-11 02:28
Articles in Press	2023-10-11 02:28
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-11-06 10:12
Publish the Manuscript Online	2023-11-15 13:46

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Long non-coding RNA CDKN2B-AS1 promotes hepatocellular carcinoma progression via E2F transcription factor 1/G protein subunit alpha Z axis
Manuscript Source	Unsolicited Manuscript
All Author List	Zhi-Gang Tao, Yu-Xiao Yuan and Guo-Wei Wang
Funding Agency and Grant Number
Corresponding Author	Guo-Wei Wang, MD, MM, Attending Doctor, Department of Radiology, Hangzhou Xixi Hospital, No. 2 Hengbu Street, Xihu District, Hangzhou 310012, Zhejiang Province, China. wanguowei6987@126.com
Key Words	Hepatocellular carcinoma; CDKN2B-AS1; E2F transcription factor 1; G protein subunit alpha Z; Proliferation
Core Tip	The high expression of long non-coding RNAs CDKN2B-AS1 in hepatocellular carcinoma (HCC) predicts poor prognosis of the patients, as it facilitates some malignant biological behaviors of HCC cells, including enhanced viability, proliferation, cell cycle progression, and anti-apoptosis ability. This study reveals one mechanism of CDKN2B-AS1 promoting HCC progression, which is the interaction between CDKN2B-AS1 and E2F transcription factor 1 in HCC cells to promote the expression of the oncogene G protein subunit alpha Z.
Publish Date	2023-11-15 13:46
Citation	Tao ZG, Yuan YX, Wang GW. Long non-coding RNA CDKN2B-AS1 promotes hepatocellular carcinoma progression via E2F transcription factor 1/G protein subunit alpha Z axis. World J Gastrointest Oncol 2023; 15(11): 1974-1987
URL	https://www.wjgnet.com/1948-5204/full/v15/i11/1974.htm
DOI	https://dx.doi.org/10.4251/wjgo.v15.i11.1974

Full Article (PDF)	WJGO-15-1974-with-cover.pdf
Full Article (Word)	WJGO-15-1974.docx
Manuscript File	86515_Auto_Edited-JLW.docx
Answering Reviewers	86515-Answering reviewers.pdf
Audio Core Tip	86515-Audio core tip.m4a
Biostatistics Review Certificate	86515-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	86515-Conflict-of-interest statement.pdf
Copyright License Agreement	86515-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document	86515-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	86515-Language certificate.pdf
Peer-review Report	86515-Peer-review(s).pdf
Scientific Misconduct Check	86515-Bing-Wang JJ-2.png
Scientific Editor Work List	86515-Scientific editor work list.pdf
CrossCheck Report	86515-CrossCheck report.pdf